grant
CRCNS: Multimodal integration for spatial navigation
Organization COLUMBIA UNIVERSITY HEALTH SCIENCESLocation NEW YORK, UNITED STATESPosted 5 Dec 2024Deadline 30 Nov 2029
NIHUS FederalResearch GrantFY2026Animal ModelAnimal Models and Related StudiesAnimalsAtmosphereBehaviorBehavioralBrainBrain Nervous SystemCell BodyCell Communication and SignalingCell SignalingCellsCognitiveColorComplexCuesDataDrosophilaDrosophila genusEncephalonEyeEyeballFliesGoalsHeadInsectaInsectsInsects InvertebratesInstructionIntracellular Communication and SignalingInvestigationKnowledgeLearningLocationMapsMemoryModelingNerve CellsNerve UnitNeural CellNeurocyteNeuronsPathway interactionsPatternPhysiologicPhysiologicalPlayProcessRoleSensoryShapesSignal TransductionSignal Transduction SystemsSignalingSiteSpace PerceptionSpatial DiscriminationSpecific qualifier valueSpecifiedStimulusStreamStructureSunlightSynapsesSynapticSystemTestingVisualWorkbiological signal transductioncognitive functionconnectomeconnectome dataconnectomic dataexperimentexperimental researchexperimental studyexperimentsflexibilityflexibleflyfruit flygene manipulationgenetic manipulationgenetically manipulategenetically perturbinterestmodel of animalmulti-modalitymultimodalitymultisensoryneural circuitneural circuitryneurocircuitryneuronalpathwayperceptual spatial orientationpolarized lightpresynapticresponsesensory integrationsensory mechanismsocial rolespatial integrationspatial navigationspatial orientationspatial perceptionsun lightsynapsesynaptic circuitsynaptic circuitrythe sunway findingwayfinding
Description preview
Spatial orientation is a fundamental cognitive function required for survival. To navigate, an animal must
know its location and its heading. The neurons thought to underlie the sense of direction are known as
head-direction cells, which respond maximally when an animal is facing in a particular direction.
Collectively, these cells form a…
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