Could disrupted functional connectivity between the hippocampus and the prefrontal cortex be an early marker of vascular cognitive impairment in demen
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The healthy blood-brain barrier (BBB) maintains selective permeability and controls cerebral blood flow to ensure efficient energy supply, prompt waste removal, and balance chemical composition in the interstitial fluid. By doing so, BBB maintains a homeostatic micro-environment in the brain which is essential for neuronal signalling and normal…
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