grant

Cortical odor processing for social recognition

Organization MONELL CHEMICAL SENSES CENTERLocation PHILADELPHIA, UNITED STATESPosted 1 Jan 2024Deadline 31 Dec 2028
NIHUS FederalResearch GrantFY2026ASDAdaptive BehaviorsAddressAffectAmentiaAnimalsAreaAutismAutistic DisorderBehaviorBehavioralBiologicalBrainBrain Nervous SystemCRE RecombinaseCalciumCalibrationCell Communication and SignalingCell SignalingChemicalsClassificationCodeCoding SystemCognitive DiscriminationComplexCuesDREADDsDegenerative Neurologic DisordersDementiaDevelopmentDiscriminationDiseaseDisinhibitionDisorderEarly Infantile AutismElectrodesElementsEncephalonEnterobacteria phage P1 Cre recombinaseEnvironmentEvolutionFeedbackFiberFoundationsGeneticGoalsHeadHouse miceHumanImageImpairmentIn VitroInbred StrainIndividualInfantile AutismIntracellular Communication and SignalingInvestigationKanner's SyndromeKnowledgeMeasuresMiceMice MammalsModern ManMurineMusMus musculusNasalNasal Passages NoseNerve CellsNerve UnitNervous System Degenerative DiseasesNeural CellNeural Degenerative DiseasesNeural degenerative DisordersNeurocyteNeurodegenerative DiseasesNeurodegenerative DisordersNeurodevelopmental DisorderNeurologic Degenerative ConditionsNeurological Development DisorderNeuronsNeuropeptide ReceptorNeurosciencesNoseOcytocinOdorsOlfactionOlfactory CortexOlfactory PathwaysOlfactory dysfunctionOlfactory systemOutcomeOxytocinOxytocin ReceptorParaventricular Hypothalamic NucleusPartner in relationshipPatientsPerformancePhotometryPopulationPopulation DynamicsPropertyRecombinant OxytocinResearchResearch ResourcesResourcesRespiratory System, Nose, Nasal PassagesRoleSamplingSensorySignal TransductionSignal Transduction SystemsSignalingSmellSmell PerceptionSocial BehaviorSocial Behavior DisordersSocial EnvironmentSocial IdentificationSocial IdentitySocial InteractionSourceStimulusSystemSystematicsTestingTimeTrainingViralVolatilizationWorkadaptation behavioradaptive behaviorautism spectral disorderautism spectrum disorderautistic spectrum disorderbacteriophage P1 recombinase Crebehavior responsebehavioral responsebiologicbiological signal transductiondegenerative diseases of motor and sensory neuronsdegenerative neurological diseasesdensitydesigner receptors exclusively activated by designer drugsdevelopmentalendomicrosopeexperimentexperimental researchexperimental studyexperimentsfitnessflexibilityflexibleimagingimprovedinsightmatemicroendoscopeneuralneural circuitneural circuitryneurocircuitryneurodegenerative illnessneurodevelopmental diseaseneuronalnovelodor discriminationodor perceptionolfactory bulbolfactory circuitryolfactory circuitsolfactory impairmentolfactory perceptionoperationoperationsoptogeneticsparaventricular nucleuspiriform cortexpreferenceprocessing speedresponsesexsmell discriminationsocialsocial climatesocial contextsocial groupsocial observationssocial rolesociobehaviorsociobehavioralsocioenvironmentsocioenvironmentalsynaptic circuitsynaptic circuitrytranslation to humans
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PROJECT SUMMARY
The sense of olfaction allows animals to gather critical information about resources, dangers, and potential social

interactions. A primary goal of olfactory neuroscience is to understand how neural circuit operations in the main

olfactory system parse chemical signals in the environment and contribute to adaptive behavior. Neural…

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