grant

Core C: Pathology and Immunobiology Core

Organization UNIV OF NORTH CAROLINA CHAPEL HILLLocation CHAPEL HILL, UNITED STATESPosted 5 Aug 1997Deadline 31 Aug 2029
NIHUS FederalResearch GrantFY2025After CareAfter-TreatmentAftercareAnatomic SitesAnatomic structuresAnatomyAssayB7-H3B7H3Basic ResearchBasic ScienceBioassayBiologicalBiological AssayBiological Specimen BanksBiological Substance BanksBiopsyBloodBlood Reticuloendothelial SystemBody TissuesBreastBreast CancerBreast Cancer ModelBreast Cancer PatientBreast Tumor PatientBreast tumor modelCAR T cell therapyCAR T therapyCD276CD276 geneCancer ModelCancerModelCancersCell BodyCell IsolationCell SegregationCell SeparationCell Separation TechnologyCellsCellular AssayClinicalClinical ResearchClinical SciencesClinical StudyClinical TrialsCollaborationsCollectionComprehensive Cancer CenterCytometryDevelopmentDoctor of PhilosophyEvaluationFISH TechnicFISH TechniqueFISH analysisFISH assayFacultyFlow CytofluorometriesFlow CytofluorometryFlow CytometryFlow MicrofluorimetryFlow MicrofluorometryFluorescence In Situ HybridizationFluorescent in Situ HybridizationFormalinFreezingFresh TissueGeneticGenetic EngineeringGenetic Engineering BiotechnologyGenetic Engineering Molecular BiologyGenomicsH and EHematoxylin and EosinHematoxylin and Eosin Staining MethodHospitalsHumanImageImage AnalysesImage AnalysisImmuneImmune MonitoringImmunesImmunobiologyImmunochemical ImmunologicImmunocompetentImmunofluorescenceImmunofluorescence ImmunologicImmunogeneticsImmunohistochemistryImmunohistochemistry Cell/TissueImmunohistochemistry Staining MethodImmunologicImmunologic MonitoringImmunologicalImmunological MonitoringImmunologicallyImmunologicsImmunologyImmunomonitoringImmunophysiologyIn Situ HybridizationInvestigatorsLaboratoriesLeadershipMalignant Breast NeoplasmMalignant NeoplasmsMalignant TumorMedicalMedicineMicrobiologyModern ManMolecularMorphologyNorth CarolinaOperative ProceduresOperative Surgical ProceduresOrganoidsPDX modelParaffin EmbeddingParticipantPathologistPathologyPatient derived xenograftPh.D.PhDPopulation SciencesProceduresProcessProtocolProtocols documentationRNA SeqRNA sequencingRNAseqRecombinant DNA TechnologyResearchResearch PersonnelResearch SpecimenResearchersResource SharingSamplingScientistServicesSingle cell seqSiteSlideSpecimenSpecimen HandlingSpecimen ProcessingSurgicalSurgical InterventionsSurgical ProcedureTNBCTechnical ExpertiseTissue ArraysTissue BanksTissue ChipTissue CollectionTissue MicroarrayTissue ProcurementsTissue repositoryTissuesTrainingTranslational ResearchTranslational ScienceTumor Tissueanti-cancer researchassay developmentbiologicbiological specimen repositorybiosample repositorybiospecimen bankbiospecimen repositorybreast pathologycancer epidemiologycancer microenvironmentcancer researchcell assaycell sortingchimeric antigen receptor (CAR) T cell therapychimeric antigen receptor T cell therapychimeric antigen receptor T therapycomputer imagingdevelopmentaldigitaldigital imagingflow cytophotometrygenetically engineeredhuman tissueimage evaluationimage interpretationimagerimagingimmune competentimmune microenvironmentimmunosuppressive microenvironmentimmunosuppressive tumor microenvironmentin situ Hybridization Geneticsin situ Hybridization Staining Methodindividuals with breast cancerinterestmalignancymalignant breast tumormammary cancer modelmammary tumor modelmedical collegemedical schoolsmouse modelmurine modelneoplasm/cancerpatient derived xenograft modelpatients with breast cancerperson with breast cancerpost treatmentresponseschool of medicinesingle cell next generation sequencingsingle cell sequencingspatial RNA sequencingspatial gene expression analysisspatial gene expression profilingspatial resolved transcriptome sequencingspatial transcriptome analysisspatial transcriptome profilingspatial transcriptome sequencingspatial transcriptomicsspatially resolved transcriptomicsspatio transcriptomicsspecimen bankspecimen repositorysuccesssurgerytechnical skillstissue preparationtranscriptome sequencingtranscriptomic sequencingtranslation researchtranslational genomicstranslational investigationtriple-negative breast cancertriple-negative invasive breast carcinomatumortumor immune microenvironmenttumor microenvironmenttumor-immune system interactionswhole slide imaging
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Core C: Pathology - Abstract
The UNC Breast SPORE Pathology and Immunobiology Core (PIC) supports and enhances cancer-related
translational, clinical, population and basic science research. The PIC provides SPORE participants with a
centralized, coordinated, quality-controlled, quality-assured facility for the procurement, processing, storage,
and…

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Core C: Pathology and Immunobiology Core — UNIV OF NORTH CAROLINA CHAPEL HILL | UNITED STATES | Aug 1997 | Dev Procure