grant
Core B: Molecular Pathology and Bioinformatics Core
Organization SLOAN-KETTERING INST CAN RESEARCHLocation NEW YORK, UNITED STATESPosted 3 Sept 2024Deadline 31 Aug 2029
NIHUS FederalResearch GrantFY2025AACRAllelic LossAmerican Association of Cancer ResearchB-raf-1BRAFBRAF geneBioinformatics coreBioinformatics research coreBioinformatics resource coreBody TissuesCancer CenterCancersClinicalClonalityCollaborationsDNADNA mutationDataDeoxyribonucleic AcidDiagnosisDoctor of PhilosophyERBB2ERBB2 geneExpression SignatureGENIEGene Expression ProfileGenetic ChangeGenetic defectGenetic mutationGenomicsGoalsHER -2HER-2HER2HER2 GenesHER2/neuImageImmune mediated therapyImmunologically Directed TherapyImmunotherapyIndividualInstitutionKnowledgeLoss of HeterozygosityMalignant NeoplasmsMalignant TumorMethodsMolecularMolecular AnalysisMutationNEU OncogeneNEU proteinNon-Polyadenylated RNANormal TissueNormal tissue morphologyNucleic AcidsOncogene ErbB2OutcomePathologyPathway interactionsPatient SelectionPatientsPh.D.PhDPopulationProtocolProtocols documentationR-Series Research ProjectsR01 MechanismR01 ProgramRAFB1RNARNA Gene ProductsRNA SeqRNA sequencingRNAseqRecurrenceRecurrentResearchResearch GrantsResearch Project GrantsResearch ProjectsResearch SpecimenResolutionRetrievalRibonucleic AcidRunningSamplingScanningSiteSlideSpecimenStandardizationStatistical MethodsSupervisionTKR1TestingTissue SampleTissuesUnderrepresented GroupsUnderrepresented PopulationsVariantVariationWorkbio-informatics pipelinebioinformatics pipelinec-erbB-2c-erbB-2 Genesc-erbB-2 Proto-Oncogenescancer typecancers that are rarecheck point immunotherapycheck point inhibitor therapycheck point inhibitory therapycheck point therapycheckpoint immunotherapycheckpoint inhibitor therapycheckpoint inhibitory therapycheckpoint therapydata sharingdepositorydigital pathologydriver lesiondriver mutationerbB-2 Genesexome sequencingexome-seqexpression subtypesgene expression patterngene expression signaturegenome mutationgenomic platformherstatinimagingimmune check point therapyimmune checkpoint therapyimmune therapeutic approachimmune therapeutic interventionsimmune therapeutic regimensimmune therapeutic strategyimmune therapyimmune-based therapiesimmune-based treatmentsimmuno therapyindividualized cancer careindividualized oncologymalignancymembermolecular pathologymolecular sub-typesmolecular subsetsmolecular subtypesmultiomicsmultiple omicsneoplasm/cancerneu Genesnovelpanomicspathology imagingpathwaypatient subclasspatient subclusterpatient subgroupspatient subpopulationspatient subsetspatient subtypespersonalized oncologyprecision cancer careprecision cancer medicineprecision oncologyrare cancerrare malignancyrare tumorrepositoryresolutionsresponsestatistic methodstissue preparationtranscriptional profiletranscriptional signaturetranscriptome sequencingtranscriptomic sequencingtranscriptomicstumorunder representation of groupsunder represented groupsunder represented peopleunder represented populationsunderrepresentation of groupsunderrepresented peoplev-raf Murine Sarcoma Viral Oncogene Homolog B1
Description preview
CORE B ABSTRACT
Molecular Pathology and Bioinformatics Core
Core Director: Michael Berger, PhD (MSK)
The Molecular Pathology and Bioinformatics Core will work closely with all Project teams to coordinate the
procurement and analysis of patient-derived tumor and matched normal tissue prioritized for further
characterization to fulfill the Research…
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