grant
Control of biomolecular systems to guide cell phenotypes
Organization PENNSYLVANIA STATE UNIVERSITY, THELocation UNIVERSITY PARK, UNITED STATESPosted 1 Apr 2026Deadline 31 Jan 2031
NIHUS FederalResearch GrantFY2026AreaBiologic ModelsBiologicalBiological MarkersBiological ModelsCell BodyCell DifferentiationCell Differentiation processCellsCollaborationsComputing MethodologiesData BasesDatabasesDevelopmentFeedbackInduction of ApoptosisInterventionKnowledgeLettersMethodsModel SystemModelingOutcomePathway interactionsPhenotypePopulationProtocolProtocols documentationResearchSpecific qualifier valueSpecifiedSystemTherapeuticTimeValidationbio-markersbiologicbiologic markerbiological systemsbiomarkercellular differentiationcombinatorialcomputational methodologycomputational methodscomputational suitecomputer based methodcomputer methodscomputing methodcontrol theorydata basedevelopmentalexperimentexperimental researchexperimental studyexperimentsnovelpathwayprogramstoolvalidations
Description preview
Project Summary/Abstract
Phenotype control, an active area of research in network control, is applicable to interacting
biomolecular systems and can identify targeted interventions that lead to desired cell phenotypes.
Phenotype control distinguishes itself from classical control theory in that (i) its objectives are
related to dynamical…
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