grant

Continued Development and Maintenance of the UltraScan Software

Organization UNIVERSITY OF MONTANALocation MISSOULA, UNITED STATESPosted 1 Aug 2016Deadline 31 Jul 2028
NIHUS FederalResearch GrantFY2025100+ years oldAIDS VirusAPBA1APBA1 geneAcquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome VirusAddressAdoptionAlgorithmsAmyloid Beta A4 Precursor Protein-Binding, Family A, Member 1AnisotropyArchitectureAutomationBiochemistryBiological ChemistryBiomedical ResearchBiophysicsBiopolymersCancersCellular biologyCentenarianCodeCoding SystemCollaborationsCommunitiesComplexComputer softwareD9S411EDataData AnalysesData AnalysisData ProtectionData SecurityData awarenessDegenerative Neurologic DisordersDevelopmentDiseaseDisorderDrug TargetingDrugsElectronicsEngineering / ArchitectureEnsureFundingFutureHIVHigh Performance ComputingHourHuman Immunodeficiency VirusesInfrastructureIntuitionInvestigationKineticsLAV-HTLV-IIILIN10LaboratoriesLibrariesLicensingLinuxLymphadenopathy-Associated VirusMINT1MUNC18-1-Interaction ProteinMacromolecular StructureMaintenanceMalignant NeoplasmsMalignant TumorManagement Information SystemsMedicationMethodsModernizationMolecularMolecular ConfigurationMolecular ConformationMolecular StereochemistryMolecular StructureNational Institutes of HealthNervous System Degenerative DiseasesNetwork-basedNeural Degenerative DiseasesNeural degenerative DisordersNeurodegenerative DiseasesNeurodegenerative DisordersNeurologic Degenerative ConditionsNeutronsOperating SystemOwnershipPharmaceutical PreparationsPropertyPublicationsRampReactionReportingReproducibilityResearchResearch ResourcesResolutionResourcesRoentgen RaysScienceScientific PublicationServicesSingle Crystal DiffractionSocial Support SystemSoftwareStructureSupercomputingSupport SystemSystemTechniquesTherapeuticTrainingUnited States National Institutes of HealthUpdateVertebrate LIN10 HomologVirus-HIVWorkX Ray CrystallographiesX-RadiationX-Ray CrystallographyX-Ray Diffraction CrystallographyX-Ray RadiationX-Ray/Neutron CrystallographyX-rayX11X11-AlphaX11-αXrayXray Crystallographyage related pathwaysaging associated mechanismaging mechanismaging pathwayaging related mechanismaging related pathwaysanalytical ultracentrifugationarchive dataarchiving dataautomated analysisbasebasesbeamlinebiological mechanism of agebiological pathways of agebiophysical analysisbiophysical foundationbiophysical principlesbiophysical sciencesbiophysical studiescell biologycentenarian human (100+)code developmentconformationconformationalconformational stateconformationallyconformationsdata acquisitiondata acquisitionsdata archivedata archivesdata interpretationdata sharingdegenerative diseases of motor and sensory neuronsdegenerative neurological diseasesdensitydesigndesigningdevelopmentaldrug/agentelectronicelectronic deviceexperimentexperimental researchexperimental studyexperimentsflexibilityflexiblehigh throughput analysishigh-end computingimprovedinformation securityinstrumentintuitivemacromolecular assemblymalignancymaterials sciencemechanism regulating agingmechanisms involved in agingmiddlewaremodel-based simulationmodels and simulationnanoscienceneoplasm/cancerneurodegenerative illnessnext generationnovelopen sourceoperationoperationspathway involved in agingpatient safetyprotocol developmentresolutionssimulationstructural biologysuper computingsupercomputertherapeutic agent developmenttherapeutic developmenttooluser protection
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Project Summary/Abstract
We propose to continue development and support for the free and open source UltraScan-III (US3) software

suite and develop new code and methods to address challenging biomedical research questions that can be

solved with the latest instruments available for analytical ultracentrifugation and at beamlines for small-angle…

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