grant
Computational Modeling of Mouse Forelimb Movements
Organization UNIVERSITY OF COLORADO DENVERLocation Aurora, UNITED STATESPosted 1 May 2025Deadline 31 Mar 2028
NIHUS FederalResearch GrantFY20263-D3-Dimensional3DAnimal ModelAnimal Models and Related StudiesAnimalsApoplexyArchitectureBRAIN initiativeBiomechanicsBrainBrain Nervous SystemBrain Research through Advancing Innovative Neurotechnologies initiativeBrain Vascular AccidentCerebellar DiseasesCerebellar DisordersCerebellar DysfunctionCerebellar SyndromesCerebellumCerebellum DiseasesCerebral StrokeCerebrovascular ApoplexyCerebrovascular StrokeCodeCoding SystemCollaborationsColoradoCommunitiesComputational toolkitComputer ModelsComputerized ModelsComputersConnectionist ModelsCristobaliteDataDevelopmentDiseaseDisorderDissociationDocumentationDyskinesia SyndromesElectromyographyEncephalonEngineering / ArchitectureEnsureEnvironmentExhibitsExtremitiesFeedbackFiberForelimbFutureGoalsHeadHealthInvestigatorsJointsKnowledgeLaboratory miceLengthLimb structureLimbsLocationLocomotionMeasuresMedical RehabilitationMethodsMiceMice MammalsModelingMotorMotor CortexMovementMovement Disorder SyndromesMovement DisordersMurineMusMuscleMuscle TissueMusculoskeletalNational Institutes of HealthNeural Network ModelsNeural Network SimulationNeurologicNeurologicalNeurosciencesNon-TrunkParalysis AgitansParkinsonParkinson DiseasePerceptronsPersonsPhysicsPhysiologicPhysiologicalPoliciesPrimary ParkinsonismProcessProductionPublic HealthPurkinje CellsPurkinje's CorpusclesRehabilitationRehabilitation therapyResearchResearch PersonnelResearchersRunningSandSilicaSilicon DioxideStrokeStructureSystemTestingTorqueTridymiteUnited States National Institutes of HealthUniversitiesVisualizationWeightWorkafter strokeartificial neural netartificial neural networkbehavior predictionbehavioral predictionbiomechanic modelingbiomechanic simulationbiomechanicalbiomechanical modelbiomechanical modelingbiomechanical simulationbody movementbrain attackbrain controlcerebellar Purkinje cellcerebral vascular accidentcerebrovascular accidentcomputational modelingcomputational modelscomputational neural networkcomputational toolboxcomputational toolscomputational toolsetcomputer based modelscomputerized modelingcomputerized toolsdeep reinforcement learningdesigndesigningdevelopmentaldisabilityeffective therapyeffective treatmentexperimentexperimental researchexperimental studyexperimentsinjuredinnovateinnovationinnovativekinematic modelkinematicsmodel of animalmotor controlmouse modelmurine modelmuscularneuralneural controlneural net architectureneural network architectureneural regulationneuromodulationneuromodulatoryneuroregulationneurotechnologynovelopen source toolopen source toolkitoptimal control theorypost strokepoststrokerehab therapyrehabilitativerehabilitative therapyresponsesensory inputsimulationstrokedstrokessynthetic neural networktheoriesthree dimensionaltooluser-friendlyweb based interfaceweights
Description preview
Project Summary/Abstract
Mouse forelimb movements are widely studied in systems neuroscience to study healthy and injured motor
networks (e.g., after stroke or cerebellar disease). This proposal builds on our novel musculoskeletal model of
the mouse forelimb to develop free and open-source tools for the neuroscience community to extract…
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