grant

Computational methods for characterizing sources of variability in drug response

Organization STANFORD UNIVERSITYLocation STANFORD, UNITED STATESPosted 20 Sept 2024Deadline 30 Jun 2029
NIHUS FederalResearch GrantFY20253-D structure3-dimensional structure3D structureAdverse ExperienceAdverse eventAutomobile DrivingBasic ResearchBasic ScienceClinicalClinical DataCollaborationsComputerized Medical RecordComputing MethodologiesCritical PathsCritical PathwaysDataData BasesData SetDatabasesDiseaseDisorderDrug InteractionsDrug ModulationDrug TargetingDrug TherapyDrugsElectronic Medical RecordEnvironmental ExposureEpigeneticEpigenetic ChangeEpigenetic MechanismEpigenetic ProcessExplosionGene ExpressionGenesGeneticGenetic DiversityGenetic VariationGoalsHuman GeneticsIndividualKnowledgeLeadMedicationMethodsModelingMolecularMolecular TargetPathway interactionsPatientsPb elementPerformancePharmaceutical PreparationsPharmacogeneticsPharmacological TreatmentPharmacotherapyPhenotypePhysiologyProteinsProteomeResearchSideSourceTextVariantVariationWorkbiobankbiorepositorycomputational methodologycomputational methodscomputer based methodcomputer methodscomputing methoddata basedata integrationdrivingdrug interventiondrug treatmentdrug/agentepigenetic variationepigeneticallyheavy metal Pbheavy metal leadknowledgebasemedical claimsnovelpathwaypharmaceutical interventionpharmacological interventionpharmacological therapypharmacology interventionpharmacology treatmentpharmacotherapeuticsresponsescreeningscreeningsthree dimensional structure
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Drugs are approved by regulators because they are relatively safe and effective. However, there are typically unanswered basic science questions about the detailed mechanisms of action, the impacts of genetic and…

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Computational methods for characterizing sources of variability in drug response — STANFORD UNIVERSITY | UNITED STATES | | Dev Procure