grant
Comparative Genomic Studies on the Evolution of Morphological Complexity
Organization NATIONAL HUMAN GENOME RESEARCH INSTITUTELocation UNITED STATES
NIHUS FederalResearch GrantFY202521+ years oldAddressAdultAdult HumanAffinity ChromatographyAnimal ModelAnimal Models and Related StudiesAnimalsArthropodaArthropodsAtlasesBasal Transcription FactorBasal transcription factor genesBiologic ModelsBiological ModelsBiologyBiomedical ResearchBody TissuesBrachydanio rerioCell BodyCell CommunicationCell InteractionCell LineageCell-to-Cell InteractionCellsCellularityChromatinCnidariaCnidariansCodeCoding SystemCoelenterataComb JelliesCommunitiesComplexCtenophoraCtenophoresCustomDNA SequenceDanio rerioDataData SetDevelopmentDevelopmental BiologyDevelopmental GeneDiseaseDisease OutbreaksDisorderDissociationElementsEmbryo DevelopmentEmbryogenesisEmbryonic DevelopmentEndotheliumEnhancersEpithelial CellsEvolutionFunctional RNAGene Action RegulationGene ExpressionGene Expression MonitoringGene Expression Pattern AnalysisGene Expression ProfilingGene Expression RegulationGene RegulationGene Regulation ProcessGene TranscriptionGeneHomologGeneral Transcription Factor GeneGeneral Transcription FactorsGenerationsGenesGenetic MarkersGenetic TranscriptionGenomeGenomicsGlandGlutamate ReceptorHealthHomeo DomainHomologHomologous GeneHomologueHumanHuman BiologyHuman GenomeImmuneImmunesInvertebrataInvertebratesLightMapsMessenger RNAMethodsMnemiopsisModel SystemModelingModern ManMolecularMolluscaMorphologyMultiomic DataMuscle CellsMyocytesNICHDNational Institute of Child Health and Human DevelopmentNational Institutes of HealthNatural regenerationNerve CellsNerve UnitNeural CellNeural DevelopmentNeurocyteNeuronsNoncoding RNANontranslated RNANormal CellOrganOrganismOrthologOrthologous GeneOutbreaksPatternPattern FormationPhotoradiationPhylogenetic AnalysisPhylogeneticsPlayPolypsPopulationPositionPositioning AttributeProgenitor CellsProtein FamilyProteinsProteomeProteomicsPublishingRNA ExpressionRNA SeqRNA sequencingRNAseqRegenerationRegenerative MedicineRegulatory ElementResearchResearch ResourcesResolutionResourcesRibosomesRoleSea WalnutsShapesSisterSomatic CellSourceSpecific qualifier valueSpecifiedStem Cell ResearchSting InjuryStructureStudy modelsSupercomputingTechniquesTissuesTranscript Expression AnalysesTranscript Expression AnalysisTranscriptionTranscription Factor Proto-OncogeneTranscription factor genesTransgenic OrganismsTranslatingTreesUnited States National Institutes of HealthUntranslated RNAUpdateVertebrate AnimalsVertebratesVisualizationVisualization softwareWorkZebra DanioZebra FishZebrafishadulthoodaffinity purificationanalyze gene expressionangiogenesiscell fixingcell typecnidocytecomparative genomicscustomsdata toolsdeep learningdeep learning methoddeep learning strategydevelopmentalentire genomefeedingfull genomegene biomarkergene expression analysisgene expression assaygene expression biomarkergene manipulationgene markergene signature biomarkergenetic biomarkergenetic manipulationgenetically manipulategenetically perturbgenome annotationgenome browsergenome scalegenome sequencinggenome-widegenomewidehomeodomainhuman diseasehuman whole genomeinnovateinnovationinnovativeinsightinteractive data visualizationinteractive visualizationliving systemmRNAmalemarinemarine environmentmodel of animalmodel organismmultiple omic dataneuralneurodevelopmentneurogenesisneuronalnoncodingnovelpreservationprogenitorprogenitor biologyprogenitor cell biologyprotein structureprotein structure predictionprotein structuresproteins structureregenerateregenerativerepairrepairedresolutionssocial rolestem and progenitor biologystem cell biologystem cell studystem cellsstingsuper computingtooltranscription factortranscriptional profilingtranscriptome sequencingtranscriptomic sequencingtranscriptomicstransgenictranslational studyvertebratavisualization toolwhole genome♂
Description preview
Genomic sequencing of non-bilaterian animal species has provided invaluable insight into the molecular innovations that have fueled the outbreak of diversity and complexity in the early evolution of animals. The cnidarians are organisms unified in a single phylum based on their use of cnidocytes (stinging cells) for capturing prey and defense from…
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