grant
Commercialization Readiness for a Portable PET Insert System for Simultaneous TOF-PET and MR Brain Imaging
NIHUS FederalResearch GrantFY2026AD biological markerAD biomarkerAD dementiaAD patientsAD related biomarkerAD therapyAD treatmentAddressAdoptionAlzheimer Type DementiaAlzheimer disease dementiaAlzheimer disease treatmentAlzheimer sclerosisAlzheimer syndromeAlzheimer treatmentAlzheimer'sAlzheimer's DiseaseAlzheimer's biomarkerAlzheimer's diagnosisAlzheimer's disease biological markerAlzheimer's disease biomarkerAlzheimer's disease diagnosisAlzheimer's disease patientAlzheimer's disease related biomarkerAlzheimer's disease therapyAlzheimer's patientAlzheimer's related biomarkerAlzheimer's therapyAlzheimers DementiaAlzheimer’s biological markerAmyloidAmyloid SubstanceBedsBrainBrain NeoplasiaBrain NeoplasmsBrain Nervous SystemBrain TumorsBrain imagingCAT scanCT X RayCT XrayCT imagingCT scanCell Communication and SignalingCell SignalingCollaborationsComparative StudyComplexComputed TomographyConsultationsContrast-Enhancing LesionDedicationsDetectionDevelopmentDevicesDiagnosisDiseaseDisorderEarly DiagnosisEarly treatmentEncephalonEnhancing LesionEpilepsyEpileptic SeizuresEpilepticsFinancial HardshipFundingGadolinium-Enhancing LesionGd-Enhancing LesionGrantHeadHealth Care SystemsHybridsImageIndustrializationInternationalIntracellular Communication and SignalingLesionMR ImagingMR TomographyMRIMRI ScansMRIsMT-bound tauMagnetic Resonance ImagingMagnetic Resonance Imaging ScanMedical Imaging, Magnetic Resonance / Nuclear Magnetic ResonanceMental DepressionMental disordersMental health disordersNMR ImagingNMR TomographyNatureNeurofibrillary TanglesNeurologicNeurologicalNoiseNuclear Magnetic Resonance ImagingOrganPETPET ScanPET imagingPETSCANPETTPatientsPerformancePhasePhotonsPilot ProjectsPositron Emission Tomography Medical ImagingPositron Emission Tomography ScanPositron-Emission TomographyPrimary Senile Degenerative DementiaProceduresProductionPsychiatric DiseasePsychiatric DisorderRad.-PETRadiation exposureRadioactiveResolutionSafetyScanningSeasonsSeizure DisorderSeverity of illnessSignal TransductionSignal Transduction SystemsSignalingSpecific qualifier valueSpecifiedStructureSystemTechnologyTestingTimeTomodensitometryTranslatingUnited StatesUniversitiesValidationVisualizationWorkX-Ray CAT ScanX-Ray Computed TomographyX-Ray Computerized TomographyXray CAT scanXray Computed TomographyXray computerized tomographyZeugmatographyaccurate diagnosisbiocompatibilitybiological signal transductionbiomarker in ADbiomarker in Alzheimer'sbiomarker in Alzheimer's diseasebiomaterial compatibilitybrain MR imagingbrain MRIbrain magnetic resonance imagingbrain sizebrain visualizationcatscancerebral MR imagingcerebral MRIcerebral magnetic resonance imagingcommercializationcommercialization readinesscomputed axial tomographycomputer tomographycomputerized axial tomographycomputerized tomographyconsultationcostcost effectivedepressiondesigndesigningdevelopmentaldisease severitydosageearly detectionearly therapyeconomic hardshipeconomic strainepilepsiaepileptogenicfinancial adversityfinancial burdenfinancial distressfinancial insecurityfinancial instabilityfinancial strainfinancial stressfinancial worryfull scale manufacturinghigh definitionhigh-resolutionimagingimaging capabilitiesimprovedinsightlarge scale manufacturinglarge scale productionmanufacturemanufacturing processmass productionmeetingmeetingsmental illnessmicrotubule bound taumicrotubule-bound tauneurofibrillary degenerationneurofibrillary lesionneurofibrillary pathologynon-contrast CTnoncontrast CTnoncontrast computed tomographypatient living with Alzheimer's diseasepatient suffering from Alzheimer's diseasepatient with Alzheimer'spatient with Alzheimer's diseasepatients with ADpilot studyportabilitypositron emission tomographic (PET) imagingpositron emission tomographic imagingpositron emitting tomographyprimary degenerative dementiaproduct developmentprogramsprogression biomarkerprogression markerprototypepsychiatric illnesspsychological disorderresolutionssenile dementia of the Alzheimer typetangletautau Proteinstau factortechnology implementationtechnology validationtumors in the brainuptakevalidationsverification and validationτ Proteins
Description preview
Project Summary
Neurological and mental health disorders cost the United States more than $800 billion each year. Alzheimer’s
disease (AD) alone costs the U.S. an estimated $345 billion in 2023. The recent approval of anti-amyloid
treatments for AD underscores the urgency for early diagnosis. Accurate diagnosis of various neurological and
mental…
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