grant
Combining Brain Stimulation with Computerized Cognitive Training for MCI
Organization MEDICAL UNIVERSITY OF SOUTH CAROLINALocation CHARLESTON, UNITED STATESPosted 1 Sept 2025Deadline 31 May 2030
NIHUS FederalResearch GrantFY2025AD dementiaAccelerationAfter CareAfter-TreatmentAftercareAgeAgingAlzheimer Type DementiaAlzheimer disease dementiaAlzheimer sclerosisAlzheimer syndromeAlzheimer'sAlzheimer's DiseaseAlzheimers DementiaAmentiaAreaBehavior Conditioning TherapyBehavior ModificationBehavior TherapyBehavior TreatmentBehavioralBehavioral Conditioning TherapyBehavioral ModificationBehavioral TherapyBehavioral TreatmentBrainBrain Nervous SystemCNS plasticityCharacteristicsClinicalClinical TrialsClinical Trials DesignClinical assessmentsCognitionCognitiveCognitive DisturbanceCognitive ImpairmentCognitive declineCognitive function abnormalCombined Modality TherapyConditioning TherapyDataDegenerative Neurologic DisordersDementiaDevelopmentDevelopment PlansDiseaseDisorderDisturbance in cognitionDoctor of PhilosophyDoseDrug TherapyEarly-Stage Clinical TrialsEncephalonEnsureFellowshipFunctional MRIFunctional Magnetic Resonance ImagingFundingFutureGoalsHealth Care TechnologyHealth PsychologyHealth SciencesHealth TechnologyImpaired cognitionInterventionInvestigationInvestigatorsK23 AwardK23 MechanismK23 ProgramKnowledgeLeadMediatingMediatorMedicalMentored Patient-Oriented Research Career Development AwardMentored Patient-Oriented Research Career Development Award (K23)MentorsMentorshipMethodologyMonitorMoodsMultimodal TherapyMultimodal TreatmentNational Institutes of HealthNervous System Degenerative DiseasesNeural Degenerative DiseasesNeural degenerative DisordersNeurocognitiveNeurodegenerative DiseasesNeurodegenerative DisordersNeurologic Degenerative ConditionsNeuronal PlasticityNeuropsychologic TestsNeuropsychological TestsNeuropsychologiesNeuropsychologyNon-pharmacologic TherapyNonpharmacologic InterventionNonpharmacologic TherapyNonpharmacologic approachNonpharmacologic treatmentOutcomeParticipantPatient Self-ReportPatientsPb elementPerformancePersonsPh.D.PhDPharmacological TreatmentPharmacotherapyPhase 1 Clinical TrialsPhase I Clinical TrialsPhysical activityPhysiologic pulsePrefrontal CortexPreventionPrimary Senile Degenerative DementiaPulseQuestionnairesR-Series Research ProjectsR01 MechanismR01 ProgramRandomizedResearchResearch ActivityResearch GrantsResearch PersonnelResearch Project GrantsResearch ProjectsResearchersScientistSecondary PreventionSelf-ReportSleepSouth CarolinaStandardizationTechniquesTechnology AssessmentTestingTimeTrainingTreatment EfficacyTreatment outcomeUnited States National Institutes of HealthUniversitiesWorkacceptability and feasibilityagesanalyzing longitudinalarmbehavior interventionbehavioral healthbehavioral interventionbody sensorbody worn sensorbrain MR imagingbrain MRIbrain magnetic resonance imagingcareercareer developmentcentral nervous system plasticitycerebral MR imagingcerebral MRIcerebral magnetic resonance imagingclinical trial analysiscognitive benefitscognitive dysfunctioncognitive enhancementcognitive losscognitive processcognitive rehabcognitive rehabilitationcognitive trainingcombination therapycombined modality treatmentcombined treatmentcomputerizedconventional therapyconventional treatmentcost effectivedegenerative diseases of motor and sensory neuronsdegenerative neurological diseasesdesigndesigningdevelopmentaldigitaldigital healthdrug interventiondrug treatmentefficacious therapyefficacious treatmentevidence baseexperiencefMRIhealth dataheavy metal Pbheavy metal leadimprovedinformantinterestintervention efficacylongitudinal analysismild cognitive disordermild cognitive impairmentmulti-modal therapymulti-modal treatmentneural plasticityneurodegenerative illnessneuroplasticneuroplasticityneuropsychologicnon-drugnon-drug therapynon-drug treatmentnon-invasive brain stimulationnondrugnondrug therapynondrug treatmentolder adultolder adulthoodparticipant engagementpatient engagementpharmaceutical interventionpharmacological interventionpharmacological therapypharmacology interventionpharmacology treatmentpharmacotherapeuticsphase 1 trialphase 2 trialphase I protocolphase I trialphase II trialpost treatmentpreventpreventingprimary degenerative dementiaprimary outcomeprofessorprogramspsychosocialpsychosocial outcomepsychosocial sequelaerandomisationrandomizationrandomly assignedrepetitive transcranial magnetic stimulationresponseresponse to therapyresponse to treatmentsecondary outcomesenile dementia of the Alzheimer typesensorskillstherapeutic efficacytherapeutic responsetherapy efficacytherapy responsetranslational opportunitiestranslational potentialtreatment effecttreatment responsetreatment responsivenesstrial designwearable biosensorwearable sensorwearable sensor technology
Description preview
PROJECT SUMMARY/ABSTRACT
The proposed K23 Award will support Dr. Stephanie Aghamoosa, PhD in launching an independent program of
research developing non-pharmacological interventions for the secondary prevention of dementia. Dr.
Aghamoosa is a clinical neuropsychologist whose long-term career goal is to become a federally-funded
investigator…
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