grant
Collaborative Research: Imaging the transition: Temporal control of zygotic genome activation by the nuclear to cytoplasmic ratio
Organization University of PennsylvaniaLocation PHILADELPHIA, United StatesPosted 1 May 2026Deadline 30 Apr 2030
NSFUS FederalResearch GrantScience FoundationPA
Description preview
Early embryonic development is characterized by a dramatic transition from cellular dependence on RNAs that were in the egg prior to fertilization to RNAs produced by the embryo itself. This process is known as zygotic genome activation (ZGA). The timing of ZGA is linked to changes in cell size, specifically the ratio of nuclear content (DNA) to…
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