grant
Clinical Subject and Biospecimen Core
Organization UNIVERSITY OF CALIFORNIA, SAN FRANCISCOLocation SAN FRANCISCO, UNITED STATESPosted 1 Apr 2008Deadline 31 Mar 2028
NIHUS FederalResearch GrantFY2025Airway DiseaseApplications GrantsAreaAsthmaBiologicalBiological Specimen BanksBiological Substance BanksBritish ColumbiaBronchial AsthmaBronchoscopyCAT scanCOPDCT X RayCT XrayCT imagingCT scanCell BodyCellsCellular AssayChronic Obstruction Pulmonary DiseaseChronic Obstructive Lung DiseaseChronic Obstructive Pulmonary DiseaseClinicalClinical DataClinical ResearchClinical StudyCollectionComputed TomographyCryofixationCryopreservationCytometryDNADataData BasesDatabasesDeoxyribonucleic AcidDysfunctionEnrollmentEnsureEpithelial CellsEpitheliumFunctional disorderGene Expression MonitoringGene Expression Pattern AnalysisGene Expression ProfilingGoalsGrant ProposalsHarvestHumanIRBIRBsImageImmuneImmunesIndividualInstitutional Review BoardsInvestigatorsLinkLungLung DiseasesLung ParenchymaLung Respiratory SystemLung TissueMeasuresMessenger RNAMethodsMicroRNAsModern ManMolecularMucous body substanceMucusNIAIDNational Institute of Allergy and Infectious DiseaseNon-Polyadenylated RNAParticipantPathologyPathway interactionsPerformancePhysiopathologyProcessProteinsProtocolProtocols documentationPulmonary DiseasesPulmonary DisorderRNARNA Gene ProductsRegistriesRegulationResearchResearch PersonnelResearch ResourcesResearch SpecimenResearchersResourcesRespiratory EpitheliumRibonucleic AcidSamplingSecureSourceSpecimenStructure of parenchyma of lungStructure of respiratory epitheliumSystemTissue BanksTissue CollectionTissue repositoryTomodensitometryTranscript Expression AnalysesTranscript Expression AnalysisTranslational ResearchTranslational ScienceUniversitiesWorkX-Ray CAT ScanX-Ray Computed TomographyX-Ray Computerized TomographyXray CAT scanXray Computed TomographyXray computerized tomographyairway epitheliumanalyze gene expressionbiologicbiological specimen repositorybiosample repositorybiospecimen bankbiospecimen repositorybronchial epitheliumcatscancell assaycell bankchronic obstructive pulmonary disorderclinical phenotypeclinical significanceclinically significantcold preservationcold storagecomputed axial tomographycomputer tomographycomputerized axial tomographycomputerized tomographydata basedata depositiondata submissiondisease of the lungdisorder of the lungenrollexperienceexperimentexperimental researchexperimental studyexperimentsgene expression analysisgene expression assaygenomic datagenomic datasethuman subjecthuman tissueimaginginsightlung disordermRNAmiRNAmucousnon-contrast CTnoncontrast CTnoncontrast computed tomographynovelpathophysiologypathwayrecruitrespiratory tract epitheliumscRNA sequencingscRNA-seqsingle cell RNA-seqsingle cell RNAseqsingle cell expression profilingsingle cell transcriptomic profilingsingle-cell RNA sequencingspecimen bankspecimen repositorysuccesstissue registrytranscriptional profilingtranslation researchtranslational investigation
Description preview
CLINICAL CORE SUMMARY
The Clinical Subject and Biospecimen Processing and Analysis Core will provide a core resource that will be
required for each aim of both projects. The core will 1) conduct unique processing and novel analysis of inflated
lung specimens from individuals with and without asthma across areas with and without mucus plugs, 2)…
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