grant
Circadian regulation of cell outputs
Organization NEW YORK UNIVERSITYLocation NEW YORK, UNITED STATESPosted 1 May 2020Deadline 31 Mar 2030
NIHUS FederalResearch GrantFY2025ASDActinsAddressAdhesion MoleculeAreaAssayAutismAutistic DisorderBasal Transcription FactorBasal transcription factor genesBehaviorBehavioralBioassayBiological AssayBrainBrain Nervous SystemCNS plasticityCell Adhesion Molecule GeneCell Adhesion MoleculesCell BodyCell Communication and SignalingCell CycleCell Division CycleCell LocomotionCell MigrationCell MovementCell ShapeCell SignalingCell SizeCellsCellular MatrixCellular MigrationCellular MorphologyCellular MotilityCircadian RhythmsCodeCoding SystemCyclicityCytoskeletal SystemCytoskeletonDNA mutationDevelopmentDiseaseDisorderDrosophilaDrosophila genusEarly Gene TranscriptionsEarly Infantile AutismEncephalonEnsureEpithelial CellsFamilyFeedbackFibroblastsFliesGTP PhosphohydrolasesGTPasesGene ExpressionGene TranscriptionGeneral Transcription Factor GeneGeneral Transcription FactorsGeneticGenetic ChangeGenetic TranscriptionGenetic defectGenetic mutationGrowth AgentsGrowth FactorGrowth SubstancesGuanosine Triphosphate PhosphohydrolasesGuanosinetriphosphatasesHepatic CellsHepatic Parenchymal CellHepatocyteImmediate-Early GenesIn VitroInfantile AutismIntracellular Communication and SignalingKanner's SyndromeLiver CellsM PhaseMitosisMitosis StageMolecularMutationNerve CellsNerve UnitNervous SystemNeural CellNeurocyteNeurologic Body SystemNeurologic Organ SystemNeuronal PlasticityNeuronsNyctohemeral RhythmOutputPathway interactionsPeriodicityPhagocytosisPhysiologyPost-Translational RegulationPosttranslational RegulationProcessProteins Growth FactorsRNA ExpressionRho-associated kinaseRho-kinaseRhythmicitySchizophreniaSchizophrenic DisordersShapesSignal InductionSignal TransductionSignal Transduction SystemsSignalingSleepStructureTestingTextToyTranscriptionTranscription Factor Proto-OncogeneTranscription factor genesTwenty-Four Hour RhythmVisualizationWound Repairaddictionaddictive disorderautism spectral disorderautism spectrum disorderautistic spectrum disorderbiological signal transductioncell adhesion proteincell morphologycell motilitycentral nervous system plasticitycircadiancircadian clockcircadian pacemakercircadian processcircadian regulationcircadian rhythmicitydaily biorhythmdementia praecoxdevelopmentalflyfruit flygene regulatory networkgenome mutationguanosinetriphosphatasein vivointestinal epitheliumintracellular skeletonneural plasticityneuronalneuroplasticneuroplasticitynovelpathwaypreventpreventingprogramsrhoschizophrenicspatial and temporalspatial temporalspatiotemporaltranscription factorwound healingwound recoverywound resolution
Description preview
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Circadian clocks drive a range of rhythmic cellular outputs to control 24hr rhythms in behavior and physiology. These outputs include rhythms in cell size and shape, but the mechanisms are not well-understood.…
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