grant
Chemical Probes for Studying Stem Cells and Environmental Interactions in Aging
Organization UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGNLocation CHAMPAIGN, UNITED STATESPosted 1 Jul 2019Deadline 31 Mar 2030
NIHUS FederalResearch GrantFY2026AddressAgingAldehydesAnimalsBiological MarkersBiologyBody TissuesCell AgingCell BodyCell SenescenceCellsCellular AgingCellular SenescenceChemicalsDetectionDevelopmentEnvironmentEnzyme GeneEnzymesHealthHypoxiaHypoxicInflammationLifeMethodsMolecular ProbesNon-Invasive DetectionNoninvasive DetectionO elementO2 elementOxidative StressOxygenOxygen DeficiencyPlayPopulationProcessProgenitor CellsProxyRegenerative capacityReplicative SenescenceResearchRoleStem Cell ResearchTissuesVisualizationage associated effectsage effectage related effectsaging effectbio-markersbiologic markerbiomarkerdesigndesigningdevelopmentalhealthy aginghealthy human agingimpact of agein vivoinfluence of ageinnovateinnovationinnovativeinsightmolecular imagingmolecule imagingnew drug targetnew druggable targetnew pharmacotherapy targetnew therapeutic targetnew therapy targetnovelnovel drug targetnovel druggable targetnovel pharmacotherapy targetnovel therapeutic targetnovel therapy targetprogenitor agingprogenitor cell agingprogenitor cell functionprogenitor functionregeneration abilityregeneration capacityregenerativereplicative agingsocial rolestem and progenitor cell functionstem and progenitor functionstem cell agingstem cell functionstem cell studystem cellstool
Description preview
Project Summary / Abstract
Stem cells are critical cell populations that maintain tissue health and regenerative capacity.
Understanding the mechanisms leading to the decline of stem cell function can provide unique
insights into how their regenerative abilities can be enhanced and prolonged to facilitate healthy
aging. The environment in which…
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