Charting Patient-specific Regulators of Plasticity in Primary and Metastatic Colorectal Cancer

Bowel cancer afflicts >900,000 people worldwide and is a major source of cancer-related mortality. While surgical resection of primary bowel tumours is occasionally curative, metastases in other organs such as the liver are responsible for residual disease and ultimately patient death. Existing bowel cancer chemotherapies target fast-growing…