grant

Cerebral Small Vessel Disease and Dementia: Defining Global Resilience and Disruption in Brain Networks

Organization WAKE FOREST UNIVERSITY HEALTH SCIENCESLocation WINSTON-SALEM, UNITED STATESPosted 15 Nov 2024Deadline 31 Oct 2029
NIHUS FederalResearch GrantFY2025AD dementiaAD pathologyAD related dementiaADRDActivities of Daily LivingActivities of everyday lifeAddressAffectAge related pathologiesAgingAlzheimer Type DementiaAlzheimer disease dementiaAlzheimer risk factorAlzheimer sclerosisAlzheimer syndromeAlzheimer'sAlzheimer's DiseaseAlzheimer's and related dementiasAlzheimer's biomarkerAlzheimer's dementia and related dementiaAlzheimer's dementia or related dementiaAlzheimer's disease and related dementiaAlzheimer's disease and related disordersAlzheimer's disease biological markerAlzheimer's disease or a related dementiaAlzheimer's disease or a related disorderAlzheimer's disease or related dementiaAlzheimer's disease pathologyAlzheimer's disease patientAlzheimer's disease related dementiaAlzheimer's disease riskAlzheimer's pathologyAlzheimer's patientAlzheimers DementiaAlzheimer’s biological markerAlzheimer’s disease biomarkerAmentiaAmyloidAmyloid SubstanceAnatomic SitesAnatomic structuresAnatomyAutopsyAwardBiological MarkersBiological TestingBlood VesselsBrainBrain Nervous SystemBrain scanCapsicumCareer Development AwardsCareer Development Awards and ProgramsCareer Development Programs K-SeriesCerebral small vessel diseaseCognitionCognitive DisturbanceCognitive ImpairmentCognitive declineCognitive function abnormalComplexComputer Software ToolsComputer softwareCouplingDataData SetDementiaDetectionDiagnosisDiagnosticDiffuseDisturbance in cognitionEducational workshopElderlyEncephalonEnvironmentFoundationsFunctional MRIFunctional Magnetic Resonance ImagingFundingFutureGoalsGrantHealthImpaired cognitionInvestigatorsK-AwardsK-Series Research Career ProgramsKnowledgeLeadLesionLicensingLobarLocationMachine LearningMentorsMethodologyMethodsMicrovascular DysfunctionModelingMulti-Ethnic Study of AtherosclerosisNational Institutes of HealthNatureNeurosciencesOlder PopulationOutcomePathologicPathologyPb elementPrevalencePreventionPrimary Senile Degenerative DementiaPrincipal InvestigatorProbabilityQOLQuality of lifeReproducibilityResearchResearch Career ProgramResearch PersonnelResearchersRisk FactorsSoftwareSoftware ToolsStatistical Data AnalysesStatistical Data AnalysisStatistical Data InterpretationStructureSystemTestingTimeTrainingTraining ActivityUnited States National Institutes of HealthWorkWorkshopWritingaberrant agingabnormal agingadvanced ageage associated diseaseage associated disorderage associated impairmentage associated pathologiesage dependent diseaseage dependent disorderage dependent impairmentage dependent pathologiesage induced pathologiesage related human diseaseage-related diseaseage-related disorderage-related impairmentaged brainaging associated pathologiesaging brainaging dependent pathologiesaging induced pathologiesaging pathologiesaging processaging related pathologiesalzheimer riskbio-markersbiologic markerbiomarkerbrain MR imagingbrain MRIbrain healthbrain magnetic resonance imagingcareercerebral MR imagingcerebral MRIcerebral magnetic resonance imagingcerebral microbleedscerebral microhemorrhagecerebral small vessel disordercerebrovascular contributions to Alzheimer's diseasecerebrovascular dysfunction in Alzheimer's diseasecognitive assessmentcognitive dysfunctioncognitive losscognitive testingcohortconferenceconventiondaily living functiondaily living functionalitydata diversitydeep learningdeep learning methoddeep learning strategydevelop softwaredeveloping computer softwarediagnostic tooldiverse datadysfunctional age related changedysfunctional agingfMRIfunctional abilityfunctional capacitygeriatrichealthy aginghealthy human agingheavy metal Pbheavy metal leadimaging biomarkerimaging markerimaging-based biological markerimaging-based biomarkerimaging-based markerimpaired agingimprovedinsightmachine based learningmachine learning based methodmachine learning based modelmachine learning methodmachine learning methodologiesmachine learning modelmaladaptive agingmalleable riskmedical collegemedical schoolsmicrovascular complicationsmicrovascular diseasemodifiable riskmultidisciplinarynecropsynetwork modelsneuropathologicneuropathologicalneuropathologynovelolder adultolder adulthoodolder groupsolder individualsolder personpathological age related changespathological agingpatient living with Alzheimer's diseasepatient suffering from Alzheimer's diseasepatient with Alzheimer'spatient with Alzheimer's diseasepepperpostmortempre-clinicalpreclinicalpreservationprimary degenerative dementiaresilienceresilientschool of medicinesenile dementia of the Alzheimer typesenior citizenskillssmall vessel diseasesoftware developmentsoftware toolkitstatistical analysisstatisticsstemsummitsymposiasymposiumtooltraining moduletraining opportunitytranslational studyvascularvascular burden on Alzheimer's diseasevascular contribution to Alzheimer's Diseasevascular contributionsvascular contributions to ADvascular contributions to Alzheimer'svascular contributor to Alzheimer's diseasevascular dysfunction in ADvascular dysfunction in Alzheimer's diseasework-study
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Summary/Abstract
My goal is to establish myself as an independent biomedical researcher in brain aging and Alzheimer's disease

(AD) and AD related dementias (ADRD). My passion to build a career in aging stems from my profound desire

to help older people to maintain their functionality and quality of life. AD/ADRD are particularly interesting to me…

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Cerebral Small Vessel Disease and Dementia: Defining Global Resilience and Disruption in Brain Networks — WAKE FOREST UN | Dev Procure