grant
Cerebellar Modulation of Cognition in Psychosis
Organization BETH ISRAEL DEACONESS MEDICAL CENTERLocation BOSTON, UNITED STATESPosted 7 Jan 2019Deadline 31 Oct 2028
NIHUS FederalResearch GrantFY2026AcuteAffectAnimalsBiological MarkersBipolar Affective PsychosisBipolar DisorderBrainBrain Nervous SystemCerebellar CortexCerebellumClinical TrialsCognitionCognitiveCognitive DisturbanceCognitive ImpairmentCognitive ManifestationsCognitive SymptomsCognitive declineCognitive deficitsCognitive function abnormalDataDiagnosisDisablingDisturbance in cognitionDrugsDysfunctionEncephalonEquipmentFunctional MRIFunctional Magnetic Resonance ImagingFunctional disorderFundingFutureGoalsHallucinationsHumanImageImmediate MemoryImpaired cognitionIndividualInterventionIntervention TrialInterventional trialLinkManic-Depressive PsychosisMedicationModern ManNIMHNational Institute of Mental HealthNaturePathologyPatient RecruitmentsPatientsPerformancePersonsPharmaceutical PreparationsPhysiopathologyPopulationProgress ReportsProtocolProtocols documentationPsychosesPsychotic DisordersQOLQuality of lifeRefractoryResearchResearch ResourcesResourcesSchizophreniaSchizophrenic DisordersShort-Term MemorySymptomsTask PerformancesTechniquesTestingTimeTranscranial magnetic stimulationTranslationsVariantVariationbio-markersbiologic markerbiomarkerbipolar affective disorderbipolar diseasebipolar illnessbipolar mood disordercandidate identificationcognitive assessmentcognitive changecognitive defectscognitive dysfunctioncognitive functioncognitive losscognitive performancecognitive testingdementia praecoxdisabilitydrug/agentfMRIfunctional outcomeshigh riskimagingimprovedlongitudinal imagingmanic depressive disordermanic depressive illnessneural circuitneural circuitryneural controlneural imagingneural regulationneuro-imagingneurocircuitryneuroimagingneurological imagingneuromodulationneuromodulatoryneuroregulationnovelparticipant recruitmentpathophysiologyprocessing speedprogramspsychotic illnesspsychotic symptomsschizophrenicserial imagingsynaptic circuitsynaptic circuitrytherapeutic targettraittranslationworking memory
Description preview
PROJECT SUMMARY/ABSTRACT
Psychotic disorders including schizophrenia, bipolar disorder, and related illnesses are severe, debilitating, and
often fatal. Cognitive impairments in psychosis are among the leading predictors of disability and poor quality
of life; despite this, there are no first line interventions to target these symptoms.…
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