grant
Cellular Mechanisms of Lysosomal Damage Response
Organization UNIVERSITY OF NEW MEXICO HEALTH SCIS CTRLocation ALBUQUERQUE, UNITED STATESPosted 1 Sept 2024Deadline 31 Aug 2029
NIHUS FederalResearch GrantFY2025AddressBindingCancersCell BodyCell Communication and SignalingCell FunctionCell PhysiologyCell ProcessCell ProtectionCell SignalingCell SurvivalCell ViabilityCellsCellular FunctionCellular PhysiologyCellular ProcessClinicalCommunicable DiseasesCytoprotectionDataDegenerative Neurologic DisordersDiseaseDisorderFacultyFosteringGoalsImmune PrecipitationImmunoprecipitationInfectious DiseasesInfectious DisorderInnovative TherapyIntracellular Communication and SignalingInvestigationKnowledgeLaboratoriesLinkLysosomesMalignant NeoplasmsMalignant TumorMembraneMicroscopyMolecularMolecular InteractionNatureNervous System Degenerative DiseasesNeural Degenerative DiseasesNeural degenerative DisordersNeurodegenerative DiseasesNeurodegenerative DisordersNeurologic Degenerative ConditionsOrganellesPathogenicityPathologicPhysiologicPhysiologicalPlayPositionPositioning AttributePostdocPostdoctoral FellowProcessProtein BiosynthesisProteinsProteomicsPublicationsPublishingRNA interference screenRNAi screenRNAi-based screenRegulationResearchResearch AssociateRibosomal Peptide BiosynthesisRibosomal Protein BiosynthesisRibosomal Protein SynthesisRoleScientific PublicationSeminalSignal TransductionSignal Transduction SystemsSignalingStressSubcellular ProcessTherapeutic InterventionTransmissionWorkbiological signal transductioncareerclinical applicabilityclinical applicationcytoprotectivedegenerative diseases of motor and sensory neuronsdegenerative neurological diseaseshuman diseaseinsightintervention therapymalignancymembrane structuremultidisciplinarynatural agingneoplasm/cancerneurodegenerative illnessnormal agingnormative agingnovelpost-docpost-doctoralpost-doctoral traineeprofessorprogramsprotein synthesisresearch associatesresponsesocial rolestress granulesuccesstenure processtenure tracktransmission process
Description preview
PROJECT SUMMARY
Lysosomes are essential membrane-bound organelles that play a vital role in cellular degradation and signaling.
Damage to lysosomes can be triggered by numerous physiological and pathological conditions, significantly
threatening cellular function and survival. Consequently, lysosomal damage is associated with an array of human…
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