grant
Cell-type specific control of alcohol-associated behavior in the striatum
Organization VANDERBILT UNIVERSITYLocation Nashville, UNITED STATESPosted 1 Aug 2025Deadline 31 Jul 2028
NIHUS FederalResearch GrantFY2025Absolute ethanolAbstinenceAction PotentialsAddressAffectAlcohol Chemical ClassAlcohol DrinkingAlcohol consumptionAlcoholsAnimalsAreaBAC cloneBACsBacterial Artificial ChromosomesBehaviorBehavioralBrainBrain Nervous SystemCNS plasticityCalciumCell BodyCell Communication and SignalingCell SignalingCellsChronicCorpus StriatumCorpus striatum structureCuesD2 receptorDRD2 ReceptorDataDependenceDiseaseDisorderDopamine D2 ReceptorDopamine ReceptorDysfunctionETOHElectrophysiologyElectrophysiology (science)EncephalonEtOH drinkingEtOH useEthanolEthyl AlcoholFunctional disorderGlutamatesGoalsGrain AlcoholHeavy DrinkingHistoryImageImplantInhalationInhalingIntracellular Communication and SignalingL-GlutamateLearningLearning DisordersMeasuresMedialMethylcarbinolMiceMice MammalsModelingMotivationMurineMusNegative ValenceNerve CellsNerve UnitNeural CellNeurocyteNeuronal PlasticityNeuronsNeurophysiology / ElectrophysiologyNucleus AccumbensOutcomeParaventricular Nucleus of ThalamusParaventricular Thalamic NucleusPhysiologicPhysiologicalPhysiologyPhysiopathologyPopulationPrefrontal CortexPrevalenceProbabilityProcessPropertyRecording of previous eventsRecurrent diseaseRelapseRelapsed DiseaseResolutionRewardsSelf AdministeredSelf AdministrationSignal TransductionSignal Transduction SystemsSignalingSliceStimulusStriate BodyStriatumStructure of paraventricular nucleus of thalamusSymptomsSynapsesSynapticThinkingTimeTrainingTransgenic MiceVisualizationWithdrawalWorkabstaining from alcoholabstaining from ethanolabstinence from alcoholabstinence from ethanolaccess to alcoholalcohol abstinencealcohol accessalcohol accessibilityalcohol availabilityalcohol cuealcohol effectalcohol exposedalcohol exposurealcohol ingestionalcohol intakealcohol interventionalcohol product usealcohol related cuealcohol responsealcohol seekingalcohol seeking behavioralcohol usealcohol use disorderalcoholic beverage consumptionalcoholic drink intakeawakebiological signal transductioncell typecentral nervous system plasticitychronic EtOH drinkingchronic alcohol consumptionchronic alcohol drinkingchronic alcohol ingestionchronic alcohol usechronic ethanol consumptionchronic ethanol drinkingchronic ethanol ingestioncostdrink heavilydrinkingdrinking behaviorefficacious therapyefficacious treatmentelectrophysiologicalendomicrosopeethanol abstinenceethanol accessibilityethanol availabilityethanol consumptionethanol cueethanol drinkingethanol effectethanol exposedethanol exposureethanol ingestionethanol intakeethanol product useethanol responseethanol seekingethanol useethanol use disorderethanol-seeking behaviorexcessive alcohol consumptionexcessive alcohol ingestionexcessive alcohol intakeexcessive drinkingexcessive ethanol ingestionexposed to alcoholexposed to ethanolexposure to alcoholexposure to ethanolextreme drinkingglutamatergicheavy alcohol usehistoriesimagingin vivolenslenseslong-term abstinencemicroendoscopeneuralneural circuitneural circuitryneural mechanismneural plasticityneurocircuitryneuromechanismneuronalneuroplasticneuroplasticityoptogeneticspatch clamppathophysiologypopulation basedpostsynapticpresynapticprevent relapsepromoterpromotorreceptor expressionrelapse preventionresolutionsresponseresponse to alcoholresponse to ethanolsegregationstriatalsynapsesynaptic circuitsynaptic circuitrythoughtstreatment strategyvapor
Description preview
Project Summary
Alcohol Use Disorder (AUD) is a learning disorder in which alcohol alters neural circuits, causing a maladaptive
desire to seek and take alcohol. AUD can develop following repeated exposure, initiating a cycle of excessive
alcohol consumption, periods of abstinence, and relapse. Despite the prevalence and cost of this disorder,…
🔒
Start 7-day free trial — $29.99/mo →Full details available on the Agency plan
Unlock the complete grant description, eligibility criteria, contract value, evaluation details and apply link — plus alerts, pipeline tracking, and CSV export.
Agency Plan
7-day free trialUnlock procurement & grants
Upgrade to access active tenders from World Bank, UNDP, ADB and more — with email alerts and pipeline tracking.
$29.99 / month
- 🔔Email alerts for new matching tenders
- 🗂️Track tenders in your pipeline
- 💰Filter by contract value
- 📥Export results to CSV
- 📌Save searches with one click