grant

Cell Biology Core

Organization UNIVERSITY OF CHICAGOLocation CHICAGO, UNITED STATESPosted 1 Dec 1996Deadline 31 Mar 2028
NIHUS FederalResearch GrantFY2025AddressAdipocytesAdipose CellB9 endocrine pancreasBeta CellBeta Cell NeoplasmBeta Cell Neoplasm of the PancreasBeta Cell Tumor of the PancreasBiologicalBiomedical ResearchBlood NeutrophilBlood Polymorphonuclear NeutrophilBody TissuesBrachydanio rerioCalcium Ion SignalingCalcium SignalingCell BodyCell LineCellLineCellsCellular biologyChicagoCircadian RhythmsCollaborationsD-GlucoseDanio rerioData AnalysesData AnalysisDevelopmentDextroseDiabetes MellitusDiseaseDisorderEducationEducation and TrainingEducational aspectsEndocrineEndocrine PancreasEnsureEnvironmentFat CellsFatty AcidsGeneticGenomicsGlucoseGoalsHealthHepatic CellsHepatic Parenchymal CellHepatocyteHumanIllinoisImmuneImmunesIndividualInsulin CellInsulin ResistanceInsulin Secreting CellInsulin deficiencyInsulin-Producing Neoplasm of the Islet CellsInsulin-Producing Tumor of the Islet CellsInsulomaInvestigatorsIslands of LangerhansIslet CellIslets of LangerhansLipocytesLiver CellsMacrophageMarrow NeutrophilMature LipocyteMature fat cellMeasurementMetabolicMethodsMiceMice MammalsMissionModelingModern ManMurineMusNesidioblastsNeutrophilic GranulocyteNeutrophilic LeukocyteNyctohemeral RhythmPancreatic Beta Cell Insulin Producing NeoplasmPancreatic Beta Cell Insulin Producing TumorPancreatic Beta Cell TumorPancreatic IsletsPars endocrina pancreatisPatientsPhysiologicPhysiologicalPhysiologyPolymorphonuclear CellPolymorphonuclear LeukocytesPolymorphonuclear NeutrophilsPolyribosomesPolysomesProceduresRenal CellResearchResearch DesignResearch PersonnelResearchersRodentRodentiaRodents MammalsRoleServicesStrains Cell LinesStudentsStudy TypeSystemT-CellsT-LymphocyteTechniquesTechnologyTestingTimeTissuesTrainingTraining and EducationTwenty-Four Hour RhythmUniversitiesZebra DanioZebra FishZebrafishadipogenesisbeta-Cell Adenomabeta-Cell Tumorbiologiccell biologycircadian processcircadian rhythmicitycultured cell linedaily biorhythmdata interpretationdevelopmentaldiabetesdiabeticdiabetogenicexperimentexperimental researchexperimental studyexperimentsextracellular vesiclesglucose uptakeiPSiPSCiPSCsimmune imagingimmunoimagingimprovedin vivoinduced pluripotent cellinduced pluripotent stem cellinducible pluripotent cellinducible pluripotent stem cellinsulin resistantinsulin secretioninsulin signalinginsulin toleranceinsulinomainvestigator trainingisletkidney celllipid biosynthesislipogenesismembermigrationnanostringneutrophilnon-diabeticnondiabeticoxidationsocial rolestudy designsynergismthymus derived lymphocyteuptakeβ-cellβ-cellsβCell
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PROJECT SUMMARY – CELL BIOLOGY CORE
Cell Biology has been a component of the DRTC since its inception in 1977. It has taken many forms over the

past 40 years, most recently focusing on studies of pancreatic islets and beta cells. However, in recent years

and, continuing in this application, the Cell Biology Core has been expanded to also include…

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Cell Biology Core — UNIVERSITY OF CHICAGO | UNITED STATES | Dec 1996 | Dev Procure