grant
CEGS: Center for Synthetic Regulatory Genomics - Renewal
Organization NEW YORK UNIVERSITY SCHOOL OF MEDICINELocation NEW YORK, UNITED STATESPosted 12 Jun 2018Deadline 29 Feb 2028
NIHUS FederalResearch GrantFY2025AI basedAffectAnimal ModelAnimal Models and Related StudiesAnimalsBase PairingBehaviorBindingBiochemicalBioethicsBiomedical EthicsBiotechBiotechnologyBrainBrain Nervous SystemCRISPRCRISPR/Cas systemCell BodyCell LineageCellsChromatinChromosomesClustered Regularly Interspaced Short Palindromic RepeatsCodeCoding SystemCollectionCommunitiesComplexCouplingCultured CellsDevelopmentDiseaseDisorderElementsEmbryo DevelopmentEmbryogenesisEmbryonic DevelopmentEncephalonEngineeringEnhancersEnsureExposure toExpression SignatureFailureFosteringFunctional RNAGEM modelGEMM modelGWA studyGWASGene Expression ProfileGene LibraryGenesGenetically Engineered MouseGenomeGenome engineeringGenomicsGenus VanillaHaplotypesHumanHuman GeneticsHuman GenomeImageImaging technologyInvestigationInvestigatorsLengthLibrariesLightMammalian CellMapsMethodologyMiceMice MammalsMinorityModelingModern ManModificationMolecular ConfigurationMolecular ConformationMolecular InteractionMolecular StereochemistryMurineMusNoncoding RNANontranslated RNANuclearPhasePhenotypePhotoradiationPlayPositionPositioning AttributeProductionProgenitor CellsReagentRegulatory ElementResearchResearch PersonnelResearch ResourcesResearchersResolutionResourcesRoleServicesSpottingsStudentsSystemTechnologyUntranslated RNAValidationVanillaVariantVariationVisualizationWorkWritingYeastsZinc Finger DomainZinc Finger MotifsZinc Fingersartificial intelligence basedcombinatorialconformationconformationalconformational stateconformationallyconformationsdark matterdesigndesigningdevelopmentaldisease modeldisorder modelfunctional genomicsgene expression patterngene expression signaturegene locusgenetic librarygenetic locusgenetically engineered mouse modelgenetically engineered murine modelgenome wide associationgenome wide association scangenome wide association studygenomewide association scangenomewide association studygenomic locationgenomic locusgenomic predictorshuman diseasehuman modelhuman whole genomehumanized micehumanized mouseimagingimprovedinnovateinnovationinnovativemachine learning based prediction modelmachine learning based predictive modelmachine learning predictionmachine learning prediction modelmammalian genomemembermodel of animalmodel of humanmodel organismmouse modelmurine modelnew technologynoncodingnovel technologiesoutreachoutreach programpersonalization of treatmentpersonalized medicinepersonalized therapypersonalized treatmentportabilityprogramspromoterpromotorresolutionssocial rolestem cellstooltraittranscriptional profiletranscriptional signaturetranslational applicationsundergradundergraduateundergraduate studentvalidationsvariant of interestvectorwhole genome association analysiswhole genome association study
Description preview
Title: Center for Synthetic Regulatory Genomics
Abstract
The Center for Synthetic Regulatory Genomics (SyRGe) is tasked with development and
application of revolutionary technology for making dramatic, coordinated changes to
extensive gene loci in the form of Big DNAs of 50-1000 kb, which enable broad
investigation of the function of regulatory…
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