grant
Caries resistance mechanisms in high-risk Indigenous children
Organization ADA FORSYTH INSTITUTE, INC.Location Somerville, UNITED STATESPosted 4 Apr 2023Deadline 31 Mar 2028
NIHUS FederalResearch GrantFY20250-11 years oldAcidsAddressAffectAl elementAluminumAmericanBacteriaBasic ResearchBasic ScienceBindingBiochemicalBody TissuesBuccal CavityBuccal Cavity Head and NeckCadmiumCarbohydratesCariesCausalityCavitas OrisCd elementCell BodyCell Communication and SignalingCell SignalingCellsChildChild YouthChildren (0-21)ClassificationDataDental DecayDental EnamelDental PlaqueDental cariesDentinDimensionsElementsEnamelEpidemiologyEtiologyExclusionFermentationFingerprintGene ExpressionGeneralized GrowthGenesGenomicsGoalsGrantGrowthHardnessHistologyHistoryHybridsImageImaging ProceduresImaging TechnicsImaging TechniquesIn VitroIndigenousIndigenous AmericanIntracellular Communication and SignalingKnowledgeLeadLegal patentMechanicsMethodsMicrobeMicrobial BiofilmsMicrobial GeneticsMineralsMinorityModelingMolecularMolecular EpidemiologyMolecular InteractionMouthOralOral cavityOral healthParticipantPatentsPb elementPhysiologicPhysiologicalPopulationPredispositionPreventative strategyPrevention strategyPreventivePreventive strategyProductionPropertyProteinsPublic HealthRecording of previous eventsReproducibilityResearchResearch DesignResistanceRibosomal RNA GenesRiskRisk FactorsS elementS mutansS. mutansSES disparitySalivaSalivarySamplingScienceScience of Microbial GeneticsSignal TransductionSignal Transduction SystemsSignalingStandardizationStatistical Data AnalysesStatistical Data AnalysisStatistical Data InterpretationStreptococcus mutansStructureStudy TypeSulfurSusceptibilitySystematicsTaxonTestingTherapeuticTimeTissue GrowthTissuesToothTooth structureactive controlbacterial geneticsbiofilmbiofilm communitybiological signal transductioncariogenic bacteriacausationcommensal bacteriacommensal bacterial speciescrystallinitydensitydental healthdisease causationearly childhoodepidemiologicepidemiologicalexperimentexperimental researchexperimental studyexperimentsheavy metal Pbheavy metal leadhigh dimensional datahigh riskhigh risk grouphigh risk individualhigh risk peoplehigh risk populationhistoriesimaginginnovateinnovationinnovativeinsightkidsmechanicmechanicalmicrobialmicrobial interactionmicrobiomemicroorganism geneticsmicroorganism interactionmineralizationmixed species biofilmmulti-microorganism biofilmmulti-modalitymultidimensional datamultidimensional datasetsmultimodalitymultispecies biofilmnovelontogenyoral bacteriaoral commensaloral floraoral streptococcipolymicrobial biofilmpopulation basedpreventpreventingprotective factorsrRNA Genesresistance mechanismresistantresistant mechanismsaliva mediatedsocio-economic disparitysocio-economic inequalitysocio-economic inequitysocioeconomic disparitysocioeconomic inequalitysocioeconomic inequitystatistical analysisstudy designteethtooth decaytooth enameltranscriptomicsyoungster
Description preview
PROJECT SUMMARY
There is a fundamental gap in our knowledge whether natural mechanisms protect high-risk children from
caries and arise from microbial interactions of commensal bacteria in the oral cavity, or from the interplay of
microbiome and tooth, mediated by saliva. The long-term goal is to prevent early childhood caries (ECC) in
North…
🔒
Start 7-day free trial — $29.99/mo →Full details available on the Agency plan
Unlock the complete grant description, eligibility criteria, contract value, evaluation details and apply link — plus alerts, pipeline tracking, and CSV export.
Agency Plan
7-day free trialUnlock procurement & grants
Upgrade to access active tenders from World Bank, UNDP, ADB and more — with email alerts and pipeline tracking.
$29.99 / month
- 🔔Email alerts for new matching tenders
- 🗂️Track tenders in your pipeline
- 💰Filter by contract value
- 📥Export results to CSV
- 📌Save searches with one click