grant
Cannabis for Palliative Care in Cancer: A Placebo-controlled Randomized Trial of Full Spectrum Hemp-derived CBD/THC
Organization UNIVERSITY OF COLORADOLocation Boulder, UNITED STATESPosted 1 Aug 2023Deadline 31 Jul 2028
NIHUS FederalResearch GrantFY20259-ene-TetrahydrocannabinolAcuteAddressAgeAmerican Cancer SocietyAnxietyAttenuatedBloodBlood Reticuloendothelial SystemCancer PatientCancer SurvivorCancer TreatmentCancersCannabidiolCannabinoidsCannabisChemicalsCognitive DisturbanceCognitive ImpairmentCognitive declineCognitive deficitsCognitive function abnormalD9-tetrahydrocannabinolDataDelta-9-TetrahydrocannabinolDiagnosisDiseaseDisorderDisturbance in cognitionDoseDrugsEffectivenessEncapsulatedHempHourImpaired cognitionIndividualLegalLiteratureLong-Term EffectsMalignant Neoplasm TherapyMalignant Neoplasm TreatmentMalignant NeoplasmsMalignant TumorMarketingMeasuresMedicationMemoryMental DepressionMental HealthMental HygieneMoodsOutcomePainPain intensityPain interferencePainfulPalliative CarePalliative TherapyPalliative TreatmentPatientsPharmaceutical PreparationsPilot ProjectsPlacebo ControlPlacebosPlantsPolypharmacyPrevalencePreventionProliferatingPsychological HealthQOLQOL improvementQuality of lifeRadiationRandomizedReportingResearchReview LiteratureRiskRoleScientistSham TreatmentSleepSleep DisordersSleep disturbancesStandardizationStressSurvey InstrumentSurveysSymptomsTHC co-useTHC useTask PerformancesTestingTetrahydrocannabinolTetrahydrocannabinol co-useTetrahydrocannabinol useUnited StatesVariantVariationWorkaberrant sleepactive methodactive techniqueactive treatmentaffective disturbanceagesalleviate symptomameliorating symptomanti-cancer therapyattenuateattenuatescancer diagnosiscancer therapycancer-directed therapycannabis usechemobrainchemotherapychemotherapy-induced cognitive impairmentchemotherapy-related cognitive impairmentcognitive defectscognitive dysfunctioncognitive functioncognitive losscognitive taskcomfort caredecrease symptomdelta(1)-THCdelta(1)-Tetrahydrocannabinoldelta(9)-THCdelta(9)-Tetrahydrocannabinoldepressiondesigndesigningdetermine efficacydisrupted sleepdisturbance in affectdisturbed sleepdrug/agentefficacy analysisefficacy assessmentefficacy determinationefficacy evaluationefficacy examinationevaluate efficacyexamine efficacyexperienceexperimentexperimental researchexperimental studyexperimentsfewer symptomsimpaired sleepimprovedimprovements in QOLimprovements in quality of lifeinterestirregular sleeplicit opioidmalignancymarijuana usemood alterationmood and affect disturbancemood disturbancemood dysfunctionmultidrug usemultiple drug useneoplasm/canceropiate medicationopioid medicationpain reductionpalliative interventionpilot studypilot trialplacebo controlledplacebo grouppoly drug usepolydrug usepost-chemotherapy cognitive impairmentprescribed opiateprescribed opioidprescription opiateprescription opioidpsychologicpsychologicalpsychological distressquality of life improvementquality of sleeprandomisationrandomizationrandomized placebo control trialrandomized placebo controlled trialrandomly assignedreduce painreduce symptomsrelieves symptomssham groupsham therapyside effectsleep diseasessleep disruptionsleep dysfunctionsleep dysregulationsleep illnesssleep problemsleep qualitysleep/wake disruptionsleep/wake disturbancesocial rolesymptom alleviationsymptom reductionsymptom reliefsynthetic cannabinoidtrendΔ(1)-THCΔ(1)-tetrahydrocannabinolΔ(9)-THCΔ(9)-tetrahydrocannabinolΔ-9-tetrahydrocannabinolΔ9-tetrahydrocannabinol
Description preview
Project Summary
Problems with pain, sleep, and mood are common among individuals diagnosed with cancer (i.e., cancer
survivors/patients), and many are turning to cannabis for symptom relief/palliative care. Recent reviews of the
literature suggest that cannabis use can indeed provide benefit for symptoms including pain interference, pain…
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