grant

Cancer Biology Research Program

Organization UNIVERSITY OF HAWAII AT MANOALocation HONOLULU, UNITED STATESPosted 1 Jul 1997Deadline 31 Jul 2029
NIHUS FederalResearch GrantFY2025AddressAdolescentAdolescent YouthAdvanced CancerAdvanced Malignant NeoplasmAnalytical BiochemistryAnimalsAnti-cancer natural productsAnti-tumor Natural ProductsAntibodiesAreaAttentionAttenuatedBasic ResearchBasic ScienceBehaviorBehavior Conditioning TherapyBehavior ModificationBehavior TherapyBehavior TreatmentBehavioralBehavioral Conditioning TherapyBehavioral ModificationBehavioral TherapyBehavioral TreatmentBiochemicalBioinformaticsBiologicalBiological MarkersBiomedical ResearchBiometricsBiometryBiostatisticsBreastBreast Cancer Risk FactorCCOPCCSGCancer BiologyCancer BurdenCancer CauseCancer CenterCancer Center Support GrantCancer ControlCancer Control ScienceCancer DetectionCancer EtiologyCancer InductionCancer Prevention InterventionCancer TreatmentCancersCaringCatchment AreaCausalityCharacteristicsChemicalsChemistryClassificationClinicClinicalClinical InvestigatorClinical ResearchClinical StudyClinical TrialsCollaborationsCommunitiesCommunity Clinical Oncology ProgramCommunity OncologyConditioning TherapyConduct Clinical TrialsCore FacilityCyanotoxinDNA MethylationDevelopmentDiagnosisDiagnosticDietDirect CostsDoctor of PhilosophyDrug TherapyDrug resistanceDrugsEarly DiagnosisElectronic cigaretteEngineeringEnvironmental ExposureEtiologyExposure toFatsFatty acid glycerol estersFosteringFundingGI microbiomeGeneralized GrowthGenesGeneticGenomicsGeographic AreaGeographic LocationsGeographic RegionGeographical LocationGeographyGoalsGrowthHawaiiHawaiianImageImmune mediated therapyImmunochemical ImmunologicImmunologicImmunologicalImmunologicallyImmunologically Directed TherapyImmunologicsImmunotherapyIncidenceInfectious AgentInstitutionIntermediary MetabolismInterventionIntra-abdominalInvadedInvestigatorsIslandKinesiologyKnowledgeLeadLife StyleLifestyleLiverMalignant CellMalignant Neoplasm TherapyMalignant Neoplasm TreatmentMalignant NeoplasmsMalignant TumorMalignant Tumor of the LungMalignant neoplasm of lungMarketingMedicationMesotheliomaMetabolicMetabolic ProcessesMetabolismMetastasisMetastasizeMetastatic LesionMetastatic MassMetastatic NeoplasmMetastatic TumorMicroscopyMissionModalityMolecularMolecular FingerprintingMolecular ProfilingMovement scienceNCI OrganizationNational Cancer BurdenNational Cancer InstituteNational Institutes of HealthNative Hawaiian and Other Pacific IslanderNative Hawaiian and Pacific IslanderNative Hawaiian or Other Pacific IslanderNative Hawaiian or Pacific IslanderNatural ProductsNatural anti-cancer agentsNatural antineoplastic agentsNatural chemotherapeutic agentsNatural chemotherapeutic productsNatural product anti-neoplasticsNeoplasm MetastasisNicotineNicotine DependenceNutritionNutsObesityObesity associated cancerObesity related cancerOutcomePacific IslandsPathologyPathway interactionsPatient CarePatient Care DeliveryPatientsPatternPb elementPh.D.PhDPharmaceutical PreparationsPharmaciesPharmacological TreatmentPharmacotherapyPharmacy facilityPhasePopulationPopulation GroupPopulation SciencesPositionPositioning AttributePreventative strategyPrevention programPrevention strategyPreventivePreventive strategyProcessPrognosisPsychosocial Assessment and CarePublicationsPulmonary CancerPulmonary malignant NeoplasmQOLQuality of lifeResearchResearch ActivityResearch PersonnelResearchersResource SharingRiskRisk BehaviorsRisk FactorsRisky BehaviorRoleScientific PublicationScreening for cancerSecondary NeoplasmSecondary TumorServicesSkinSmokingStrategic PlanningSurvivorsSystematicsTM-MKRTechnologyTestingTherapeuticTherapeutic Clinical TrialTherapeutic InterventionTissue GrowthTobaccoTobacco ConsumptionTobacco useTranslatingTranslational ResearchTranslational ScienceTreatment outcomeTumor MarkersUnited States National Institutes of HealthUniversitiesVisceralVisceral fatVulnerable PopulationsWorkabdominal adiposityabdominal fatadiposityaging biological markeraging biomarkeraging markeranti-cancer researchanti-cancer therapyat risk behaviorattenuateattenuatesbehavior interventionbehavioral interventionbio-markersbiobehaviorbiobehavioralbiologicbiologic markerbiomarkerbiomarker developmentbiomarker discoverybiomarker drivenbiomarker identificationbiomarker validationbreast cancer riskcancer biomarkerscancer cellcancer educationcancer epidemiologycancer markerscancer metastasiscancer preventioncancer researchcancer riskcancer survivalcancer therapycancer typecancer-directed therapycarcinogenesiscare for patientscare of patientscaring for patientscausationclinical applicabilityclinical applicationclinical diagnosticsclinical practicecollegecollegiatecorpulencedemographicsdevelop therapydevelopmentaldietsdifferences in healthdigestive tract microbiomedisease causationdrug discoverydrug interventiondrug resistantdrug sensitivitydrug treatmentdrug/agente-cige-cig usee-cigarettee-cigarette useearly cancer detectionearly detectionecigecig useecigaretteecigarette useelectronic cigarette useenteric microbiomeepigenetic biomarkerepigenetic markerepigenomicsexperiencegastrointestinal microbiomegeographic sitegut microbiomegut-associated microbiomehealth differenceheavy metal Pbheavy metal leadhepatic body systemhepatic organ systemhigh dimensional datahigh risk grouphigh risk individualhigh risk peoplehigh risk populationidentification of biomarkersidentification of new biomarkersimage-based methodimagingimaging methodimaging modalityimmune therapeutic approachimmune therapeutic interventionsimmune therapeutic regimensimmune therapeutic strategyimmune therapyimmune-based therapiesimmune-based treatmentsimmuno therapyimprovedinfectious organisminformatics toolinnovateinnovationinnovativeinsightinter-institutionalintervention developmentintervention effectintervention therapyintestinal biomeintestinal microbiomejuvenilejuvenile humanlung cancermalignancymarker identificationmarker validationmedical collegemedical diagnosticmedical schoolsmembermethylation biomarkermethylation markermolecular profilemolecular signaturemortalitymultidimensional datamultidimensional datasetsmultidisciplinarynaturally occurring productneoplasm/cancernew anti-cancer agentnew anticancer agentnew anticancer drugnew antineoplasticnew cancer drugnew drug targetnew drug treatmentsnew druggable targetnew drugsnew markernew pharmacological therapeuticnew pharmacotherapy targetnew therapeutic targetnew therapeuticsnew therapynew therapy targetnext generation therapeuticsnicotine addictionnicotine dependentnovelnovel anti-cancer agentnovel anti-cancer drugnovel anticancer agentnovel anticancer drugnovel antineoplasticnovel biomarkernovel cancer drugnovel drug targetnovel drug treatmentsnovel druggable targetnovel drugsnovel markernovel pharmaco-therapeuticnovel pharmacological therapeuticnovel pharmacotherapy targetnovel therapeutic targetnovel therapeuticsnovel therapynovel therapy targetobesity riskontogenypathwaypharmaceutical interventionpharmacological interventionpharmacological therapypharmacology interventionpharmacology treatmentpharmacotherapeuticspre-clinicalpreclinicalpreventpreventingprognosticprognosticationprogramspsychosocial assessmentpsychosocial carepsychosocial studiespsychosocial supportradiomicsregional differenceresistance to Drugresistant to Drugresponseresponse to therapyresponse to treatmentrisk for obesityrisk of obesityschool of medicinescreeningscreening cancer patientsscreeningssmall moleculesocialsocial cultural factorsocial culture determinantsocial determinantssocial rolesociocultural determinantsociocultural factorsociodeterminantsynergismtargeted drug therapytargeted drug treatmentstargeted therapeutictargeted therapeutic agentstargeted therapytargeted treatmenttherapeutic responsetherapy developmenttherapy responsetobacco product usetooltranslation researchtranslational applicationstranslational cancer researchtranslational clinical trialtranslational investigationtranslational opportunitiestranslational potentialtreatment developmenttreatment responsetreatment responsivenesstumor biomarkertumor cell metastasistumor initiationtumor specific biomarkeruptakevulnerable groupvulnerable individualvulnerable people
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CANCER BIOLOGY - ABSTRACT
Basic and translational cancer research is essential to advancing our understanding of cancer development

and progression. New mechanistic insights provide new tools and strategies for cancer prevention, diagnosis,

and therapy. The Cancer Biology Program (CB) studies fundamental cellular, molecular, genetic,…

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