Cancer associated fibroblasts in squamous cancer: Coupling transcriptional heterogeneity with pathological matrix dynamics
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Cancer associated fibroblasts (CAFs) are a central component of every tumour microenvironment that can either promote or inhibit cancer progression. Recent advances in single cell sequencing revealed an astonishing functional CAF heterogeneity, which is influenced by their mechanical microenvironment. Currently the coupling between the molecular /…
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