grant
Calculating the Components of Work of Breathing in Neonates with Bronchopulmonary Dysplasia
Organization CINCINNATI CHILDRENS HOSP MED CTRLocation CINCINNATI, UNITED STATESPosted 15 Aug 2024Deadline 30 Jun 2029
NIHUS FederalResearch GrantFY202521+ years oldAddressAdmissionAdmission activityAdrenal Cortex HormonesAdultAdult HumanAgeAirAirway ResistanceAlbuterolAlveolarBody TissuesBreathingBronchiBronchial-Dilating AgentsBronchodilator AgentsBronchodilatorsBronchopulmonary DysplasiaCaringCharacteristicsChest WallChest wall structureChildhoodChildren's HospitalCicatrixClinicalClinical TreatmentCongenital laryngeal stridorCorticoidsCorticosteroidsDiseaseDisorderDistalDoseDrug usageElasticityFibrosisFutureGestationGoalsHealthHealth Care CostsHealth CostsIndividualInfantInflammationInterventionInvoluntary MuscleLiquid substanceLocationLungLung ComplianceLung DiseasesLung ParenchymaLung Respiratory SystemLung TissueLung Volume MeasurementsMR ImagingMR TomographyMRIMRIsMagnetic Resonance ImagingMeasuresMedical Imaging, Magnetic Resonance / Nuclear Magnetic ResonanceMedical centerMedicineMembraneMethodsModelingNMR ImagingNMR TomographyNeonatalNeonatal Intensive Care UnitsNewborn Intensive Care UnitsNuclear Magnetic Resonance ImagingObstructionPathologyPatientsPediatric HospitalsPhenotypePopulationPrecision carePregnancyPremature BirthPremature InfantPrematurely deliveringPreterm BirthProventilPulmonary DiseasesPulmonary DisorderPulmonary imagingReaderRelaxationResearchResistanceRespirationRespiratory AirflowRespiratory AspirationRespiratory DiseaseRespiratory InspirationRespiratory System DiseaseRespiratory System DisorderRespiratory distressRiskSalbutamolScarsSeverity of illnessSiteSmooth MuscleSpecific qualifier valueSpecifiedSteroid CompoundSteroidsStructure of parenchyma of lungSymptomsTechniquesThoracic WallTissuesTitrationsTracheaTrachea ProperTracheobronchomalaciaTranslatingTreesUnited StatesVentolinWorkWork of BreathingZeugmatographyadulthoodagesairflow limitationairflow obstructionairway limitationairway obstructionchronic lung disease in infantschronic lung disease in neonatal infantschronic lung disease in neonateschronic lung disease in newbornschronic lung disease in prematuritychronic lung disease in preterm infantschronic lung disease of infancychronic lung disease of prematurityclinical interventionclinical therapycommon treatmentcustomized therapycustomized treatmentdisease of the lungdisease phenotypedisease severitydisorder of the lungdrug useevidence baseextreme prematurityextremely premature infantextremely pretermextremely preterm infantfluidimproved outcomeindividualized careindividualized medicineindividualized patient careindividualized patient treatmentindividualized therapeutic strategyindividualized therapyindividualized treatmentinfant chronic lung diseaseinfants born prematureinfants born prematurelyinfants with chronic lung diseaseinnovateinnovationinnovativeinspirationlaryngomalacialiquidlumen dilatorlung disorderlung imaginglung pressurelung scanningmembrane structureneonatal ICUneonatal chronic lung diseaseneonatenewborn chronic lung diseasenovelobstructed airflowobstructed airwaypatient responsepatient specific responsepatient specific therapiespatient specific treatmentpediatricpersonalized carepersonalized diagnosispersonalized diagnosticspersonalized patient carepost-prematurity respiratory diseaseprecise diagnosticsprecision diagnosticsprecision medicineprecision-based medicinepremature babypremature childbirthpremature deliverypremature infant humanpremature neonatespremature newbornpreterm babypreterm deliverypreterm infantpreterm infant humanpreterm infants with chronic lung diseasepreterm neonatepreterm newbornpulmonary pressurereconstructionresistantrespiratoryrespiratory airway obstructionrespiratory mechanismresponseresponsive patientsimulationtailored medical treatmenttailored therapytailored treatmenttooltracheomalaciatrial regimentrial treatmentunique treatmentvery prematurevery pretermwindpipe
Description preview
Project Summary
Neonates can now survive premature birth from as early as 22 weeks’ gestation, but often suffer from bron-
chopulmonary dysplasia (BPD) – chronic lung disease of prematurity. BPD consists of several phenotypes –
hyperdense lung consisting of fibrotic tissue or inflammation, hyperinflated airspaces, and airway collapse at
various…
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