grant

Building and Implementing Best Practices for Buprenorphine Initiation in the Setting of Fentanyl Use

Organization UNIVERSITY OF WASHINGTONLocation SEATTLE, UNITED STATESPosted 15 Aug 2023Deadline 31 Jul 2028
NIHUS FederalResearch GrantFY2025Absence of pain sensationAbsence of sensibility to painActiqAdanonAlthoseAssess implementationAwardAwarenessBuprenorphineCaringCertificationCessation of lifeClinicalCommunitiesComplexConsensusCounselingCountryDataData CollectionDeathDolophineDoseDrugsDuragesicEffectivenessEnrollmentFDA approvedFailureFeedbackFeels no painFentanestFentanylFentylFundingFutureGoalsHospitalsImplementation assessmentIndividualInpatientsInterviewInvestigatorsLifeLiteratureMedical centerMedicationMethadoneMethadoseMethodsMorbidityMorbidity - disease rateNalorexNaltrexoneNatureNemexinNo sensitivity to painOpiate agonistOpiate receptor agonistOpiatesOpioidOpioid agonistOpioid receptor agonistOut-patientsOutcomeOutpatientsPatient CarePatient Care DeliveryPatientsPenetrationPersonsPharmaceutical PreparationsPhasePhentanylPhysiciansPilot ProjectsPractice GuidelinesPreparationPrevalenceProceduresProcessProviderQualitative MethodsQualitative ResearchRandomizedReViaReactionResearchResearch MethodologyResearch MethodsResearch PersonnelResearch SupportResearch TrainingResearchersRespiratory DepressionReview LiteratureRiskRuralSafetySecondary toSubstance Use DisorderTimeTrainingTreatment FailureVentilatory DepressionVivitrolWaiting ListsWithdrawalWorkaddictionaddictive disorderanalgesiabarriers to implementationcare for patientscare of patientscareercaring for patientsclinician factorsclinician-level factorsdepressed breathingdepression of breathingdrug/agenteffectiveness/implementation hybrid studyeffectiveness/implementation studyenrollevaluate implementationevaluation of implementationevidence baseexperiencefacilitators to implementationfeasibility testingfentanyl useimplementation barriersimplementation challengesimplementation evaluationimplementation facilitatorsimplementation scienceimprovedimproved outcomeinnovateinnovationinnovativelipophilicitymedication for opioid use disordermortalitymultidisciplinarynovelopiate consumptionopiate drug useopiate intakeopiate useopiate use disorderopioid consumptionopioid drug useopioid intakeopioid useopioid use disorderoverdose deathoverdose fatalitiesphysician factorsphysician-level factorspilot studypreferencepreparationsprovider factorsprovider-level factorsqualitative reasoningrandomisationrandomizationrandomly assignedrecruitrelative effectivenessresearch and methodsresponsesafety netsubstance use and disordertherapy failuretoolvirtualwaitlist
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PROJECT SUMMARY
Morbidity and mortality related to opioid use continue to rise, with fentanyl now the most

common opioid involved in overdose death. Despite three FDA approved medications for opioid

use disorder (MOUD)—methadone, buprenorphine, and naltrexone--as many as 3 out of 4

people with OUD are not on any of these lifesaving medications,…

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Building and Implementing Best Practices for Buprenorphine Initiation in the Setting of Fentanyl Use — UNIVERSITY OF WAS | Dev Procure