grant
BLRD Research Career Scientist Award Renewal
Organization PORTLAND VA MEDICAL CENTERLocation PORTLAND, UNITED STATESPosted 1 Oct 2021Deadline 30 Sept 2028
VANIHUS FederalResearch GrantFY2025ASCVDAlabamaAnimal ModelAnimal Models and Related StudiesArmed Forces PersonnelAtherosclerosisAtherosclerotic Cardiovascular DiseaseAwardBasal Transcription FactorBasal transcription factor genesBlood VesselsBody TissuesCalcifiedCardiovascular DiseasesCell BodyCell FunctionCell PhysiologyCell ProcessCell ReprogrammingCellsCellular FunctionCellular PhysiologyCellular ProcessCircadian DysregulationCollaborationsDevelopmentDiabetes MellitusFundingGene Action RegulationGene Expression RegulationGene RegulationGene Regulation ProcessGeneral PopulationGeneral PublicGeneral Transcription Factor GeneGeneral Transcription FactorsGoalsGrantHealthHealth Care CostsHealth CostsHyperglycemiaInterventionInvestigationInvestigatorsKO miceKnock-out MiceKnockout MiceLeiomyocyteMacrophageMedical centerMentorsMilitaryMilitary PersonnelMissionMolecularMolecular TargetMφNational Institutes of HealthNull MouseOxidative StressPathogenesisPatient CarePatient Care DeliveryPhenotypePhysiciansPostdocPostdoctoral FellowPreventative strategyPrevention strategyPreventive strategyProgenitor CellsQOLQuality of lifeR-Series Research ProjectsR01 MechanismR01 ProgramRegulationResearchResearch AssociateResearch GrantsResearch PersonnelResearch Project GrantsResearch ProjectsResearchersRoleScientistServicesSmooth Muscle CellsSmooth Muscle MyocytesSmooth Muscle Tissue CellSubcellular ProcessTherapeuticTissuesTrainingTranscription Factor Proto-OncogeneTranscription factor genesTranslatingUnited States National Institutes of HealthUniversitiesUpregulationVascular DiseasesVascular DisorderVascular Smooth MuscleVascular agingVascular calcificationVeteransatheromatosisatherosclerotic diseaseatherosclerotic vascular diseaseblood vessel disorderbonecalcificationcardiovascular disordercardiovascular healthcare for patientscare of patientscareercaring for patientscellular reprogrammingcircadian abnormalitycircadian clockcircadian disruptioncircadian disturbancecircadian dysfunctioncircadian impairmentcircadian pacemakerdevelopmentaldiabetesdiabeticgene functiongraduate studenthyperglycemicimprovedinnovateinnovationinnovativeinsightknockout genelife spanlifespanmilitary populationmodel of animalmouse modelmurine modelnew drug targetnew druggable targetnew pharmacotherapy targetnew therapeutic targetnew therapy targetnext generationnovelnovel drug targetnovel druggable targetnovel pharmacotherapy targetnovel therapeutic targetnovel therapy targetosteogenicpost-docpost-doctoralpost-doctoral traineeprogramsresearch associatessocial rolestem cellstranscription factorvascularvascular dysfunctionvasculature agingvasculopathy
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Project Summary/Abstract
My major research focus is to understand the fundamental mechanisms of gene regulation and function in the
development of cardiovascular disease, a major health burden for our veterans. Our overarching goals are to
translate the findings into identification of novel molecular targets and strategies for prevention and…
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