grant
BLRD Research Career Scientist Award Application
Organization RLR VA MEDICAL CENTERLocation INDIANAPOLIS, UNITED STATESPosted 1 Oct 2023Deadline 30 Sept 2028
VANIHUS FederalResearch GrantFY2025AcademiaAdverse effectsAffectAgeAgingAlcohol DrinkingAlcohol consumptionAmericanAnimal ModelAnimal Models and Related StudiesAreaAwardBiological MarkersBiologyBiopsyBody TissuesBone FormationBone ResorptionBone TissueBone remodelingBone structureBook ChaptersBooksCardiac DiseasesCardiac DisordersCareer MobilityCell FunctionCell PhysiologyCell ProcessCellular FunctionCellular PhysiologyCellular ProcessCessation of lifeChronicChronic Kidney FailureChronic Renal DiseaseChronic Renal FailureClinicalClinical ResearchClinical SciencesClinical StudyCollagenDeathDeath RateDiabetes MellitusDiseaseDisorderDrug TherapyEndocrinologyEtOH drinkingEtOH useFractureFutureFuture GenerationsGeneral PopulationGeneral PublicGeneralized GrowthGoalsGrantGrowthHealthHeart DiseasesHigh PrevalenceHistologicHistologicallyHospital AdmissionHospitalizationHumanHydrationHydration statusIACUCImpairmentIncubatorsIndianaIndividualInstitutionInstitutional Animal Care and Use CommitteeIntermediary MetabolismInternationalInvestigatorsJournalsKidneyKidney Urinary SystemLaboratoriesLife StyleLifestyleMagazineMechanicsMentorsMetabolic ProcessesMetabolismMetabolism and EndocrinologyMicroRNAsMineralsModern ManModificationMorphologyMusculoskeletalNational Institutes of HealthNephrologyOsteoclastic Bone LossOsteogenesisOsteoporosisOutcomePTSDPatientsPersonsPharmacological TreatmentPharmacotherapyPopulationPorosityPost-Traumatic NeurosesPost-Traumatic Stress DisordersPosttraumatic NeurosesPrevalenceProcessPublicationsPublishingQOL improvementRegimenResearchResearch PersonnelResearch ResourcesResearchersResourcesRiskRisk FactorsRoleScientific PublicationScientistServicesSkeletonSmokingSocial Support SystemSocietiesSocioeconomically disadvantagedStudentsStudy SectionSubcellular ProcessSupport SystemTestingTextbooksTissue GrowthTissuesTranslational ResearchTranslational ScienceTreatment EfficacyUnderrepresented GroupsUnderrepresented PopulationsUnited States National Institutes of HealthVeteransWorkWorkforce Developmentagesalcohol ingestionalcohol intakealcohol product usealcohol usealcoholic beverage consumptionalcoholic drink intakeassociate facultyassociate professorbio-markersbiologic markerbiomarkerbonebone fracturebone fragilitybone lossbone preservationbone qualitybone tissue formationbone turnovercare givingcareercareer advancementcareer transitioncaregivingchronic kidney diseaseclinical investigationclinical relevanceclinically relevantdeath riskdesigndesigningdiabetesdrug interventiondrug treatmentearly-career facultyeditorialefficacy testingethanol consumptionethanol drinkingethanol ingestionethanol intakeethanol product useethanol useexperienceexperimentexperimental researchexperimental studyexperimentsfracture riskheart disorderhigh schoolhuman tissueimprovedimprovements in QOLimprovements in quality of lifeindexingintervention efficacylack of physical activitymechanicmechanicalmechanical propertiesmedical collegemedical schoolsmembermiRNAmid-career facultymidcareer facultymilitary veteranmodel of animalmortalitymortality ratemortality ratiomortality risknano indentationnanoindentationnew approachesnew markernext generationnovel approachesnovel biomarkernovel markernovel strategiesnovel strategyontogenyopiate consumptionopiate drug useopiate intakeopiate useopioid consumptionopioid drug useopioid intakeopioid usepharmaceutical interventionpharmacological interventionpharmacological therapypharmacology interventionpharmacology treatmentpharmacotherapeuticsphysical inactivitypost-trauma stress disorderposttrauma stress disorderpre-clinical studyprecision medicineprecision-based medicinepreclinical studyprogramsquality of life improvementrenalschool of medicineskeletalskeletal structureskeletal tissueskeletonssocial rolesocio-economic disadvantagesocio-economically disadvantagedsocio-economically underprivilegedsocioeconomic disadvantagesocioeconomically underprivilegedtargeted drug therapytargeted drug treatmentstargeted therapeutictargeted therapeutic agentstargeted therapytargeted treatmenttherapeutic efficacytherapy efficacytranslation researchtranslational investigationtranslational opportunitiestranslational potentialtraumatic neurosisunder representation of groupsunder represented groupsunder represented peopleunder represented populationsunderrepresentation of groupsunderrepresented peopleveteran population
Description preview
The prevalence of chronic kidney disease (CKD) in our veterans puts them at elevated risk of fracture and
fracture-associated death. Nearly 1 of every 3 veterans has CKD, fracture risk in persons with CKD is 4x higher
than the age-matched general population, and persons who fracture with CKD have longer hospitalization and
higher mortality rates…
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