grant
BLRD Research Career Scientist Award Application
Organization JESSE BROWN VA MEDICAL CENTERLocation CHICAGO, UNITED STATESPosted 1 Apr 2020Deadline 31 Mar 2030
VANIHUS FederalResearch GrantFY2025AcylationAlkynesApoplexyAutoregulationAwardBile AcidsBindingBloodBlood PlasmaBlood Reticuloendothelial SystemBrain Vascular AccidentCardiovascular DiseasesCell BodyCellsCerebral StrokeCerebrovascular ApoplexyCerebrovascular StrokeChemistryCholalic AcidsCholesterolCholesterol HomeostasisCholic AcidsCollaborationsComplexCoronary DiseaseCoronary heart diseaseDNA MethylationDiabetes MellitusDietDisciplineDiseaseDisorderDisseminated SclerosisDisulfidesDoctor of PhilosophyDysfunctionEducationEducational aspectsEducational process of instructingElementsEpigeneticEpigenetic ChangeEpigenetic MechanismEpigenetic ProcessEpithelial CellsEquilibriumFaceFatty AcidsFunctional disorderFutureGeneral PopulationGeneral PublicGoalsGrantGuidelinesHCVHCV infectionHCV therapyHCV treatmentHb SS diseaseHbSS diseaseHealthHemoglobin S DiseaseHemoglobin sickle cell diseaseHemoglobin sickle cell disorderHepaticHepatic DisorderHepatitis C TherapeuticsHepatitis C TherapyHepatitis C Virus TreatmentHepatitis C treatmentHepatitis C virusHepatitis C virus infectionHigh PrevalenceHomeostasisHypercholesteremiaInflammatory Bowel DiseasesInflammatory Bowel DisorderInjury to LiverInstitutionIntestinalIntestinesInvestigatorsLDL CholesterolLDL Cholesterol LipoproteinsLaboratoriesLeadLipidsLiverLiver diseasesLow Density Lipoprotein CholesterolMD studentsMacromolecular StructureMaintenanceMeasuresMediatingMedical StudentsMentorsMetabolicMetabolic DiseasesMetabolic DisorderMetabolic dysfunctionMethodsMiceMice MammalsMissionModificationMolecularMolecular InteractionMolecular StructureMonitorMultiple SclerosisMurineMusNAFLDNational Institutes of HealthNatureNervous System DiseasesNervous System DisorderNeurologic DisordersNeurological DisordersOrganPainPainfulPathway interactionsPatientsPb elementPh.D.PhDPhysiciansPhysiological HomeostasisPhysiologyPhysiopathologyPlasmaPlasma SerumPostdocPostdoctoral FellowPredispositionPrevalenceProcessProductionProgenitor CellsProteinsRecommendationRegulationResearchResearch AssociateResearch PersonnelResearchersReticuloendothelial System, Serum, PlasmaRiskRisk FactorsRoleScientistSickle Cell AnemiaStem Cell likeSterolsStrokeSusceptibilityTeachingTherapeuticTherapeutic InterventionThesaurismosisTimeTrainingTransgenic MiceUnited States National Institutes of HealthUniversitiesUnsaturated Fatty AcidsVeteransWorkZetiaabsorptionatherosclerosis riskatherosclerotic riskbalancebalance functionbeta-Lipoprotein Cholesterolbile acid transporterbowelbrain attackcardiovascular disease riskcardiovascular disordercardiovascular disorder riskcareercerebral vascular accidentcerebrovascular accidentcholesterol absorptioncholesterol metabolismcholesterol transporterscoronary disorderdiabetesdiabetic patientdietsepigeneticallyezetimibezetimibefacesfacialgraduate studentgut-liver axisheavy metal Pbheavy metal leadhepatic body systemhepatic damagehepatic diseasehepatic injuryhepatic organ systemhepatitis C infectionhepatopathyhigh blood cholesterolhigh riskhypercholesterolemiaimprovedinfected with HCVinfected with hepatitis Cinfected with hepatitis C virusinfection by hepatitis c virusinfection with HCVinfection with hepatitis Cinfection with hepatitis C virusinflammatory disease of the intestineinflammatory disorder of the intestineinhibitorinnovateinnovationinnovativeinsightinsular sclerosisinterestintervention therapyintestinal autoinflammationintestinal epitheliuminventionliver damageliver developmentliver disorderliver injuryluciferinmedical school studentsmetabolism disordermilitary veteranmouse modelmurine modelneurological diseasenon-alcohol fatty liver diseasenon-alcoholic fatty liver diseasenon-alcoholic liver diseasenonalcoholic fatty liver diseasenoveloverexpressoverexpressionpathophysiologypathwaypatient populationpost-docpost-doctoralpost-doctoral traineepre-docpre-doctoralprofessorprogenitor capacityprogenitor cell likeprogenitor-likeprogramsresearch associatessickle cell diseasesickle cell disordersickle diseasesicklemiasocial rolestem cell characteristicsstem cellsstem-likestemnessstrokedstrokesstudent researchstudent-led researchtherapeutic targettoolundergradundergraduateundergraduate studentuptakeveteran population
Description preview
Summary
Our Veteran population has a significantly higher prevalence of diabetes mellitus and faces an increased risk of
developing cardiovascular diseases (CVD) as compared to the general population. Stringent guidelines
recommend decreasing plasma LDL-cholesterol to very low levels in patients with high risk for atherosclerosis
and other…
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