grant

Biospecimens

Organization UNIVERSITY OF CALIFORNIA, SAN FRANCISCOLocation SAN FRANCISCO, UNITED STATESPosted 1 Sept 2002Deadline 30 Apr 2028
NIHUS FederalResearch GrantFY2025A β-42A β42A-beta 42A-beta42AD dementiaAD related dementiaADRDAbeta-42Abeta42Active Follow-upAgreementAlzheimer Type DementiaAlzheimer disease dementiaAlzheimer sclerosisAlzheimer syndromeAlzheimer'sAlzheimer's DiseaseAlzheimer's and related dementiasAlzheimer's dementia and related dementiaAlzheimer's dementia or related dementiaAlzheimer's disease and related dementiaAlzheimer's disease and related disordersAlzheimer's disease or a related dementiaAlzheimer's disease or a related disorderAlzheimer's disease or related dementiaAlzheimer's disease related dementiaAlzheimers DementiaAmyloidAmyloid SubstanceAmyloid beta-42Amyloid beta42Amyloid β-42Amyloid β42Amyloidβ-42Amyloidβ42AssayAstroproteinAβ-42Aβ42BioassayBiological AssayBiological MarkersBiological Specimen BanksBiological Substance BanksBiostatistics CoreBloodBlood PlasmaBlood Reticuloendothelial SystemBlood SerumCategoriesCell BodyCell Culture TechniquesCell LineCellLineCellsClassificationClinicalCollaborationsCollectionCommunitiesDNADataData CollectionData SetDegenerative Neurologic DisordersDeoxyribonucleic AcidDevelopmentDiseaseDisorderDysfunctionEarly DiagnosisEmotionsEpitheliumEvaluationFTD dementiaFibroblastsFrontal Temporal DementiaFrontotemporal DementiaFunctional disorderGFA-ProteinGFAPGenerationsGenesGenotypeGlial Fibrillary Acid ProteinGlial Fibrillary Acidic ProteinGlial Intermediate Filament ProteinHeterogeneityHumanImageInfrastructureInternationalInvestigatorsLaboratoriesLeadLightLiquid substanceLumbar PunctureMT-bound tauMeasurementMeasuresMissionModern ManMonitorNerve DegenerationNervous System Degenerative DiseasesNeural Degenerative DiseasesNeural degenerative DisordersNeurodegenerative DiseasesNeurodegenerative DisordersNeurologic Degenerative ConditionsNeurologistNeuron DegenerationNon-Polyadenylated RNANucleic AcidsOn-Line SystemsOnline SystemsPBMCParticipantPatientsPb elementPeripheral Blood Mononuclear CellPhotoradiationPhysiciansPhysiopathologyPlasmaPlasma SerumPositionPositioning AttributePrimary Senile Degenerative DementiaPrivatizationProceduresProcessPrognostic MarkerProteinsProteomicsR-Series Research ProjectsR01 MechanismR01 ProgramRNARNA Gene ProductsReproducibilityResearchResearch GrantsResearch PersonnelResearch Project GrantsResearch ProjectsResearch ResourcesResearch SpecimenResearch SupportResearchersResourcesReticuloendothelial System, Serum, PlasmaRibonucleic AcidSamplingScientistSerumSpecimenSpinal PunctureStagingStandardizationStrains Cell LinesSymptomsSystematicsTechnologyTestingValidationVisitWorkaccurate diagnosisactive followupaptamerbio-markersbiologic markerbiological specimen repositorybiomarkerbiomarker developmentbiomarker discoverybiomarker identificationbiosample repositorybiospecimen bankbiospecimen repositorycell bankcell culturecell culturescell preparationclinical diagnosiscultured cell linedata managementdegenerative diseases of motor and sensory neuronsdegenerative neurological diseasesdepositorydevelopmentaldiagnostic biomarkerdiagnostic markerearly detectionexperiencefluidfollow upfollow-upfollowed upfollowupfront temporal dementiafrontal lobe dementiafrontotemporal lobar degeneration dementiafrontotemporal lobar dementiafrontotemporal lobe degeneration associated with dementiaheavy metal Pbheavy metal leadiPSiPSCiPSCsidentification of biomarkersidentification of new biomarkersimagingimprovedinduced pluripotent cellinduced pluripotent stem cellinducible pluripotent cellinducible pluripotent stem cellinsightlipidomicsliquidmarker identificationmicrotubule bound taumicrotubule-bound taumolecular biomarkermolecular markerneural degenerationneural imagingneuro-imagingneurodegenerationneurodegenerativeneurodegenerative illnessneurofilamentneuroimagingneurological degenerationneurological imagingneuronal degenerationneuropathologicneuropathologicalneuropathologynew markernovelnovel biomarkernovel markeronline computerp-taup-τpathophysiologyphospho-tauphospho-τphosphorylated taupost-translational modification of tauposttranslational modification of tauprimary degenerative dementiaprognostic biomarkerprognostic indicatorprognosticationquery toolsrepositorysenile dementia of the Alzheimer typespecimen bankspecimen repositorysynergismtautau Proteinstau factortau phosphorylationtau posttranslational modificationtau-1therapeutic targettreatment effectvalidationsweb basedτ Proteinsτ phosphorylation
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PROJECT SUMMARY—BIOSPECIMENS CORE (Core G)
Fluid biomarkers hold great promise for improving early and accurate diagnosis, symptom monitoring,
prognostication, and measuring treatment effects for frontotemporal dementia (FTD). Over the past 19 years,
the UCSF PPG Biospecimens sub-core (as part of the Neuropathology Core) has successfully…

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Biospecimens — UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | UNITED STATES | Sept 2002 | Dev Procure