grant
Biomechanics of the Human Brain During High-Severity Impacts: A Multimodal Approach
Organization UNIVERSITY OF SOUTH CAROLINA AT COLUMBIALocation COLUMBIA, UNITED STATESPosted 1 Jan 2025Deadline 31 Dec 2029
NIHUS FederalResearch GrantFY20253-D3-Dimensional3DAccelerationAddressAffectAnatomic SitesAnatomic structuresAnatomyAnimalsBiomechanicsBody TissuesBrainBrain ConcussionBrain Nervous SystemBrain TraumaBrain regionCadaverCalibrationCell BodyCellsCerebral ConcussionCessation of lifeClassificationClinical ManagementCollectionCommotio CerebriComputer ModelsComputer SimulationComputer based SimulationComputerized ModelsCoupledDataData BasesData SetDatabasesDeathDevelopmentDisparateDysfunctionEncephalonEquipmentEventFiberFunctional disorderGoalsHeadHealth CareHelmetHumanImageInjuryInvestigatorsKnowledgeLinkLocationLong-term disabilityMR ImagingMR TomographyMRIMRIsMachine LearningMagnetic Resonance ImagingMapsMeasurementMeasuresMedical Imaging, Magnetic Resonance / Nuclear Magnetic ResonanceMemoryMethodsModelingModern ManMotionMotor VehiclesNMR ImagingNMR TomographyNuclear Magnetic Resonance ImagingOutcomeOutputParticipantPatternPersonsPhysiopathologyPredicting RiskPreventative measurePreventionPreventive measureProbabilityPropertyResearch PersonnelResearch SpecimenResearchersRiskSafetyScanningSeveritiesSiteSkullSpecimenSportsStretchingSystematicsTechniquesTechnologyTimeTissuesTraumatic Brain InjuryUnconsciousUnconscious StateUnconsciousnessUnited StatesValidationVariantVariationWorkZeugmatographybiomechanicalbiomechanical analysesbiomechanical analysisbiomechanical assessmentbiomechanical characterizationbiomechanical evaluationbiomechanical measurementbiomechanical profilingbiomechanical testbrain tissuecadavericcadaversclinical relevanceclinically relevantcollision sportscomputational modelingcomputational modelscomputational simulationcomputer based modelscomputer based predictioncomputerized modelingcomputerized simulationconcussionconcussiveconsciousness losscontact sportscraniumdata basedesigndesigningdevelopmentalelastic imagingelasticity imagingelastographyexperimentexperimental researchexperimental studyexperimentsforecasting riskhead impacthuman datahuman subjectimagingimprovedin vivoinjuriesinjury preventioninnovateinnovationinnovativeinsightlarge data setslarge datasetsmachine based learningmilitary operationmulti-modalitymultidisciplinarymultimodalityneuralnovelpathophysiologypoint of injurypredict responsivenesspredict riskpredict riskspredicted riskpredicted riskspredicting responsepredicting riskspredictive modelingpredictive riskpredicts riskpreventpreventingresponserisk predictionrisk predictionssimulationstructural imagingthree dimensionaltooltraumatic brain damagevalidations
Description preview
Project Summary
Traumatic brain injury (TBI) is a significant health care problem, affecting over 2.5 million people in the United
States annually. Most cases are classified as mild or concussive TBI, caused by a rapid acceleration to the skull
that may lead to short-term loss of consciousness and memory, as well as long-term disability.…
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