grant
Biomarker Core
Organization MASSACHUSETTS GENERAL HOSPITALLocation BOSTON, UNITED STATESPosted 15 May 2019Deadline 31 Mar 2029
NIHUS FederalResearch GrantFY2025AD dementiaAD related dementiaADRDAlzheimer Type DementiaAlzheimer disease dementiaAlzheimer sclerosisAlzheimer syndromeAlzheimer'sAlzheimer's DiseaseAlzheimer's and related dementiasAlzheimer's dementia and related dementiaAlzheimer's dementia or related dementiaAlzheimer's disease and related dementiaAlzheimer's disease and related disordersAlzheimer's disease or a related dementiaAlzheimer's disease or a related disorderAlzheimer's disease or related dementiaAlzheimer's disease related dementiaAlzheimers DementiaAmentiaAmyloidAmyloid SubstanceAssayBioassayBiologicalBiological AssayBiological MarkersBloodBlood BanksBlood PlasmaBlood Reticuloendothelial SystemBostonCerebrospinal FluidClinicalClinical ManagementCognitive DisturbanceCognitive ImpairmentCognitive declineCognitive function abnormalCollaborationsCommunitiesDLG4DLG4 geneDataData AnalysesData AnalysisData SetDementiaDetectionDevelopmentDiabetes MellitusDiagnosisDiagnosticDisciplineDiseaseDisorderDisturbance in cognitionDysfunctionEducationEducation and TrainingEducational aspectsEnsureEvaluationExperimental DesignsFacultyFellowshipFunctional disorderGeneticGoalsHealthHealth CareHealth Care ProfessionalHealth ProfessionalHistoryHypertensionImageImpaired cognitionIndividualInflammatoryInternationalInvestigatorsLaboratoriesLaboratory ScientistsLiquid substanceMT-bound tauMarketingMassachusettsMeasuresMedicalMental DepressionMentorshipMetabolicNAC precursorNerve DegenerationNeurologyNeuron DegenerationNutritionPARK1 proteinPARK4 proteinPSD95ParticipantPathologyPatientsPerformancePersonsPhysiatricsPhysiatryPhysical MedicinePhysiopathologyPlasmaPlasma SerumPreventionPrimary Senile Degenerative DementiaProcessPrognosisProteinsProteomicsPsychiatryQualifyingRecording of previous eventsRehabilitation MedicineRelationship-BuildingResearchResearch PersonnelResearch ResourcesResearch SpecimenResearchersResidenciesResourcesReticuloendothelial System, Serum, PlasmaRoleSAP90SNCASNCA proteinSamplingScienceScientistSpecimenStagingStudentsSynapsesSynapticSyndromeTechnologyTherapeutic ResearchTrainingTraining ProgramsTraining and EducationUniversitiesValidationVascular Hypertensive DiseaseVascular Hypertensive DisorderWorka-syna-synucleinalpha synucleinalpha synuclein genealphaSP22asynbio-markersbiobankbiologicbiologic markerbiomarkerbiomarker developmentbiorepositoryblood-based biomarkerblood-based markercandidate biomarkercandidate markercerebral spinal fluidclinical translationclinically translatablecognitive dysfunctioncognitive losscohortdata integrationdata interpretationdepressiondevelopmentaldiabetesdisease heterogeneityfluidhigh blood pressurehistorieshyperpiesiahyperpiesishypertensive diseasehypertensive disorderimaginginterestliquidmicrotubule bound taumicrotubule-bound tauneural degenerationneurodegenerationneurodegenerativeneurological degenerationneuronal degenerationneuropathologicneuropathologicalneuropathologynew markernext generationnon A-beta component of AD amyloidnon A4 component of amyloid precursornovelnovel biomarkernovel markerpathophysiologypersonalization of treatmentpersonalized medicinepersonalized therapypersonalized treatmentprimary degenerative dementiaprognosticprogramsrecruitsenile dementia of the Alzheimer typesocial rolespecific biomarkersspinal fluidstudent mentoringstudent-led learningsynapsetautau Proteinstau factortooltranslational investigatortranslational researchertranslational scientistvalidationsvascular contributionsα synuclein geneα-synα-synucleinτ Proteins
Description preview
REVISED ABSTRACT:
The Biomarker Core provides state-of-the-art biofluid processing, biobanking, and biomarker assays in blood and cerebrospinal fluid (CSF) to advance diagnostic, prognostic, mechanistic and therapeutics research for the Massachusetts ADRC (MADRC) and the broader ADRD research community. A particular interest of ours is the…
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