grant
Biomarker Core
Organization COLUMBIA UNIVERSITY HEALTH SCIENCESLocation NEW YORK, UNITED STATESPosted 26 Aug 2025Deadline 30 Jun 2030
NIHUS FederalResearch GrantFY2025Academic Medical CentersAcuteBioinformaticsBiological MarkersBlood SampleBlood SerumBlood specimenCardiacCitrullineCollaborationsCommon Rat StrainsComputational toolkitComputing MethodologiesCore FacilityDataData ReportingData ScienceData Storage and RetrievalDevicesDose RateDysfunctionEducational workshopEvaluationExposure toFunctional disorderGamma RadiationGamma RaysGastrointestinal InjuryGenesGuidelinesHeartHeart InjuriesInformaticsInfrastructureInstitutionInvestigatorsKnowledgeLaboratoriesLung damageMass Photometry/Spectrum AnalysisMass SpectrometryMass SpectroscopyMass SpectrumMass Spectrum AnalysesMass Spectrum AnalysisMeasuresMetabolicMethodologyMethodsMiceMice MammalsMissionModelingMolecularMonitorMultiomic DataMurineMusMyocardial depressionMyocardial dysfunctionNeutronsNormal TissueNormal tissue morphologyNuclearOrganOutcomePathway interactionsPatternPerformancePharmacologyPhysiopathologyPlayPrecision Medicine InitiativePredispositionProteinsProteomicsPublicationsQualifyingR-Series Research ProjectsR01 MechanismR01 ProgramRadiationRadiation InjuriesRadiation exposureRadiation therapyRadiotherapeuticsRadiotherapyRatRats MammalsRattusReproducibilityResearchResearch GrantsResearch PersonnelResearch Project GrantsResearch ProjectsResearchersResolutionResource SharingRodentRodent ModelRodentiaRodents MammalsRoentgen RaysRoleSamplingScientific PublicationSerumServicesStratificationSusceptibilitySystemTechnologyTestingToxic effectToxicitiesTrainingUniversitiesUniversity Medical CentersValidationWorkWorkshopX-RadiationX-Ray RadiationX-rayXrayanalyzing longitudinalarmbio-informatics resourcebio-markersbioinformatics resourcebiologic markerbiomarkerbiomarker arraybiomarker developmentbiomarker discoverybiomarker panelbiomarker validationcalcitonin precursor polyproteincardiac dysfunctioncardiac injurycomputational infrastructurecomputational methodologycomputational methodscomputational resourcescomputational toolboxcomputational toolscomputational toolsetcomputer based methodcomputer based predictioncomputer infrastructurecomputer methodscomputerized toolscomputing methodcomputing resourcesdata acquisitiondata acquisitionsdata hostingdata integrationdata miningdata representationdata representationsdata retrievaldata storagedataminingdesigndesigningefficacy testinggastrointestinalheart dysfunctionindustrial partnershipindustry partnerindustry partnershipinjury to organsinjury to tissueinsightinstrumentationinter-individual variabilityinter-individual variationirradiationirradiation injuryirradiation responseirradiation-induced injurylipidomicslongitudinal analysislung basal segmentlung baselung damage after radiotherapylung damage post radiationlung injurymarker panelmarker validationmetabolism measurementmetabolomicsmetabonomicsmolecular phenotypemulti-modal datamulti-modal datasetsmultimodal datamultimodal datasetsmultiomicsmultiple omic datamultiple omicsmultiple reaction monitoringnew markernovelnovel biomarkernovel markerorgan injurypanomicspathophysiologypathwaypredictive biological markerpredictive biomarkerspredictive markerpredictive modelingpredictive molecular biomarkerpredictive panelpro-calcitoninprocalcitoninprogramspulmonary damagepulmonary injurypulmonary tissue damagepulmonary tissue injuryradiation induced lung damageradiation lung injuryradiation mitigatorradiation responseradiation treatmentradiation-induced injuryradiation-induced lung injuryradiological mitigatorradiomitigatorresolutionsresponseresponse to radiationsocial rolesuccesstissue injurytooltreatment with radiationvalidationsverification and validationγ-Radiationγ-Ray
Description preview
Advances in molecular phenotyping technologies to measure inter-individual variations in genes, proteins, and
metabolites have revolutionized precision medicine initiatives in radiation research. While the field has focused
on the use of single omics to delineate biomarkers of radiation injury to X-rays or gamma rays; few have used
a multi-omics…
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