grant
Biological Mechanisms Core - RC2
Organization JOHNS HOPKINS UNIVERSITYLocation BALTIMORE, UNITED STATESPosted 1 Jun 2003Deadline 30 Jun 2028
NIHUS FederalResearch GrantFY2025AgingAmericanAngiotensinsAnimal ModelAnimal Models and Related StudiesAnimalsAreaAssayAttenuatedBioassayBiologicalBiological AgingBiological AssayBiology of AgingBiomedical EngineeringBody TissuesCausalityChronicClinicalClinical ResearchClinical StudyClinical TrialsCollaborationsCommunicationComplexDataData AnalysesData AnalysisDevelopmentDiagnosticEnergy ExpenditureEnergy MetabolismEpigeneticEpigenetic ChangeEpigenetic MechanismEpigenetic ProcessEtiologyFacultyFosteringGeneticGenomicsGerontologyGoalsHumanInflammationInflammatoryInfrastructureInstitutionInternationalInterventionInvestigatorsLaboratoriesLeadershipMeasurementMentorsMentorshipMitochondriaModalityModern ManMolecularNanotechnologyPathway interactionsPhenotypePhysiologicPhysiologicalPhysiologyPopulation StudyPreventative strategyPreventionPrevention strategyPreventivePreventive strategyProteomicsPsychological TransferResearchResearch DesignResearch PersonnelResearch ResourcesResearchersResourcesSamplingScienceStudy TypeSystemTechnologyTechnology TransferTestingTherapeuticTissue ModelTissuesTrainingTranslational ResearchTranslational ScienceTranslationsVendorage associatedage associated declineage correlatedage dependentage dependent declineage linkedage relatedage related declineage related pathwaysage specificaging associatedaging associated mechanismaging mechanismaging pathwayaging relatedaging related mechanismaging related pathwaysanimal model developmentaptamerattenuateattenuatesbio-engineeredbio-engineersbioengineeringbiologicbiological engineeringbiological mechanism of agebiological pathways of agebiological process of agebiological systemscareercausationclinical relevanceclinically relevantdata interpretationdecline in functiondecline in functional statusdecline with agedevelop therapydevelopmentaldiagnostic developmentdisease causationepigeneticallyexperiencefrailtyfunctional declinefunctional status declinegerontologichealthspanhealthy life spanhuman subjectinsightintervention developmentlate in lifelate lifelearning transfermechanism regulating agingmechanisms involved in agingmetabolism measurementmetabolomicsmetabonomicsmild cognitive disordermild cognitive impairmentmitochondrialmodel developmentmodel developmentsmodel of animalmolecular arraymouse modelmultiomicsmultiple omicsmurine modelnano technano technologynano-technologicalnanotechnanotechnologicalnew technologynext generationnovelnovel technologiesolder adultolder adulthoodpanomicspathwaypathway involved in agingpopulation-based studypopulation-level studypreventpreventingsarcopeniasarcopenicskillsstudies of populationsstudy designstudy of the populationtherapy developmenttooltraining transfertranslationtranslation researchtranslational investigationtreatment development
Description preview
Resource Core 2 (RC2) Biological Mechanisms Core: Project Summary
The identification of the etiologies of frailty and age-related vulnerability remains a crucial challenge for
gerontological research. Key to this challenge are the development of a better understanding of the underlying
biological basis that contributes to frailty and the…
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