grant
Biased randomness: a fundamental connectivity mechanism for associative brain centers.
Organization UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAHLocation SALT LAKE CITY, UNITED STATESPosted 1 Jul 2018Deadline 30 Jun 2029
NIHUS FederalResearch GrantFY2025AccountingAddressAnimalsArchitectureAssociation LearningAssociative LearningAxon TerminalsBiological FunctionBiological ProcessBionomicsBrainBrain Nervous SystemCameroonCandidate Disease GeneCandidate GeneCell BodyCellsCognitiveCote d'IvoireDevelopmentDiseaseDisorderDrosophilaDrosophila genusDrosophila melanogasterEcologyElementsEncephalonEngineering / ArchitectureEnvironmentEquilibriumEthologyEvolutionFliesFrequenciesGeneral PractitionersGeneralistsGenesGoalsIndividualInfrastructureIvory CoastKenyaLearningLobeLogicMayotteMeasuresMediationMolecularMorinda citrifoliaMushroom BodiesNegotiatingNegotiationNerve CellsNerve UnitNeural CellNeurocyteNeuronsNeurosciencesNoniOdorsOutcomePatternPavlovian conditioningPerformancePlantsPopulationPost-Transcriptional Gene SilencingPresynaptic Nerve EndingsPresynaptic TerminalsRNA InterferenceRNA SilencingRNAiRandomizedRegulationResearchSensorySequence-Specific Posttranscriptional Gene SilencingSpecialistStimulusSynapsesSynapticSynaptic BoutonsSynaptic TerminalsTestingTheoretical StudiesWorkassociative conditioningbalancebalance functionbehavior responsebehavioral responseclassical conditioningcostdesigndesigningdevelopmentalexperimentexperimental researchexperimental studyexperimentsflexibilityflexibleflyfruit flylearning abilitylearning achievementlearning competencelobesneuronalneuronal circuitneuronal circuitryolfactory stimulusperceptual stimulusphysicochemical phenomena related to the sensespresynapticrandomisationrandomizationrandomly assignedsensory stimulussynapsesynapse formationsynaptogenesis
Description preview
PROJECT SUMMARY
Uncovering fundamental mechanisms of neuronal connectivity that enable associative brain centers to learn
efficiently is an important goal of neuroscience. In the mushroom body — the associative brain center in
Drosophila melanogaster — the constituent Kenyon cells receive input from olfactory projection neurons. Each
projection…
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