grant
Beyond characterizing flavors: Effects of odorless constituents (sensory additives, solvents, and synthetic nicotine) on tobacco product use behaviors from adolescence to adulthood
Organization YALE UNIVERSITYLocation NEW HAVEN, UNITED STATESPosted 30 Sept 2013Deadline 31 Aug 2028
NIHUS FederalResearch GrantFY20251,2,3-Propanetriol1,2,3-Trihydroxypropane12-20 years old21+ years old4-hydroxy-3-methoxybenzaldehydeAddressAdolescenceAdolescentAdolescent YouthAdultAdult HumanAffectAgeAssayBehaviorBioassayBiological AssayBiological MarkersBrainBrain Nervous SystemCalciumChemicalsCigarCigaretteCommon Rat StrainsDataDependenceDopamineElectronic cigaretteEncephalonExposure toFoundationsGlycerinGlycerolGustationHuman CloningHydroxytyramineIceIntakeIrritantsLinkMaintenanceMeasuresMentholMiceMice MammalsMissionModelingMurineMusNicotineOdorsOralOutcomePerceptionPlethysmographyPrevalence StudyPropanediolsPropertyPropylene GlycolsPsychological reinforcementPublic HealthRatRats MammalsRattusReceptor ProteinReinforcementRewardsRodentRodentiaRodents MammalsRoleSelf AdministeredSelf AdministrationSensorySmokeless TobaccoSolventsStereoisomerSweetenersSweetening AgentsSystemTasteTaste BudsTaste PerceptionTestingTobaccoTobacco ConsumptionTobacco useWithdrawalYouthYouth 10-21addictionaddictive disorderadolescence (12-20)adulthoodaerosolized nicotineage associated differenceage based differenceage dependent differenceage dependent variationage differenceage related differenceage related variationage specific differenceagesbio-markersbiologic markerbiomarkercigarillosconditioningdiffer by agedifference across agedifference in agedrinkinge-cige-cig liquidse-cigarettee-cigarette liquidse-juicee-liquidecigecig liquidsecigaretteecigarette liquidsejuiceelectronic liquideliquidenantiomergenetic approachgenetic strategygustatory perceptiongustatory processinggustatory responseirritationjuvenilejuvenile humanlater in lifelater lifeneurochemicalneurochemistrynicotine consumptionnicotine rewardnicotine seekingnicotine seeking behaviornicotine usenicotine vapororal sensorypreconditioningpreferencereceptorrespiratoryresponsesexsocial rolesugarsweet tastesweet taste perceptiontaste processingtaste receptortaste responsetobacco flavortobacco product usetobacco productsvanillaldehydevanillinvaporvapor containing nicotinevaporized nicotinevariation by ageyouth age
Description preview
Project Summary/Abstract:
Characterizing flavors in tobacco products are associated with increased tobacco use initiation, reinforcement,
and difficulty quitting. In addition to characterizing flavors, tobacco products contain odorless sensory additives
such as sweeteners and synthetic cooling agents found in e-cigarettes and smokeless tobacco…
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