grant

BehavioraL ActIvation for the PreVention of Post-strokE Depression in LoW-incomE OLder Stroke Survivors (LIVE-WEL)

Organization UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTONLocation HOUSTON, UNITED STATESPosted 4 Jun 2025Deadline 30 Apr 2030
NIHUS FederalResearch GrantFY202521+ years oldActive Follow-upAdultAdult HumanAdverse effectsAffectAgingAnxietyApoplexyBehaviorBehavioralBereavementBleedingBrain Vascular AccidentCaringCerebral StrokeCerebrovascular ApoplexyCerebrovascular StrokeChronic disabilityClinicalClinical TrialsClinical effectivenessCognition TherapyCognitive DisturbanceCognitive ImpairmentCognitive PsychotherapyCognitive TherapyCognitive declineCognitive function abnormalCognitive treatmentCommunication DisordersCommunication impairmentCommunicative DisordersCounselorDataDependenceDisabled PersonsDisabled PopulationDiseaseDisorderDisturbance in cognitionDrug InteractionsDrug TherapyDrugsED visitER visitEconomic IncomeEconomical IncomeEffectivenessEmergency care visitEmergency department visitEmergency hospital visitEmergency room visitEmotional DepressionEvidence based interventionFearFinancial HardshipFrequenciesFrightFutureGeneralized Anxiety DisorderGoalsGuidelinesHAM-DHamilton Depression ScaleHamilton Rating Scale for DepressionHandicappedHealthHealth CareHealth Care CostsHealth Care ProfessionalHealth Care ProvidersHealth Care VisitHealth CostsHealth PersonnelHealth PrioritiesHealth ProfessionalHemorrhageHospital AdmissionHospitalizationImpaired cognitionImpairmentIncomeInterventionInvestigatorsIschemiaLeadLicensingLifeLow incomeMajor Depressive DisorderMeasurementMediatingMediatorMedical RehabilitationMedicationMental DepressionMental HealthMental HygieneModalityModificationMotivationNIMHNational Institute of Mental HealthNeurologic DeficitOutcomeParticipantPatientsPb elementPeople with DisabilitiesPersistent disabilityPersons with DisabilitiesPharmaceutical PreparationsPharmacological TreatmentPharmacotherapyPolypharmacyPopulationPositive ReinforcementsPreventionPreventiveProfessional counselorPsychological HealthQOLQOL improvementQuality of lifeQuestionnairesRandomized, Controlled TrialsRecoveryRecurrenceRecurrentRehabilitationRehabilitation therapyResearch PersonnelResearchersRetirementRewardsRiskRisk FactorsRisk ReductionRoleSelf EfficacyStrokeStroke preventionSuicideSurvivorsSymptomsTestingTherapeuticTimeTrainingVisitactive followupadulthoodafter strokeage associatedage correlatedage dependentage linkedage relatedage specificalleviate symptomameliorating symptomanti-depressant agentanti-depressant drugsanti-depressantsanti-depressive agentsanxiety reductionassess effectivenessavoidance behaviorblood lossbrain attackcare as usualcerebral vascular accidentcerebrovascular accidentclinical depressionclinical relevanceclinically relevantco-morbidco-morbiditycognitive behavior interventioncognitive behavior modificationcognitive behavior therapycognitive behavioral interventioncognitive behavioral modificationcognitive behavioral therapycognitive behavioral treatmentcognitive dysfunctioncognitive losscomorbiditycostcost effectivedeath riskdecrease symptomdelivered remotelydepressiondepression preventiondepression symptomdepressivedepressive symptomsdetermine effectivenessdiagnostic criteriadisabilitydisabled individualdisabled peopledisparity in healthdrug interventiondrug treatmentdrug/agenteffectiveness assessmenteffectiveness evaluationeffectiveness testingemotional distressevaluate effectivenessexamine effectivenessexperiencefatal attemptfatal suicidefeeling distressfeeling upsetfewer symptomsfinancial adversityfinancial burdenfinancial distressfinancial insecurityfinancial strainfinancial stressfollow upfollow-upfollowed upfollowupfunctional independencehealth care personnelhealth care workerhealth disparityhealth providerhealth workforceheavy metal Pbheavy metal leadhigh riskimprovedimprovements in QOLimprovements in quality of lifeincomesindexingindividuals with disabilitiesintent to dieintervention effectmajor depressionmajor depression disordermedical personnelmental trainingmortalitymortality riskold ageolder adultolder adulthoodpharmaceutical interventionpharmacological interventionpharmacological therapypharmacology interventionpharmacology treatmentpharmacotherapeuticsphysical disabilityphysically disabledphysically handicappedpost strokepost stroke depressionpoststrokepoststroke depressionpreventprevent strokepreventingprimary outcomequality of life improvementrandomized control trialreduce riskreduce risksreduce symptomsreduce that riskreduce the riskreduce these risksreduces riskreduces the riskreducing riskreducing the riskrehab therapyrehabilitativerehabilitative therapyrelieves symptomsremote deliveryresponseretirementsrisk-reducingsecondary outcomesocial rolestressorstroke survivorstrokedstrokessubthreshold depressionsuicidessymptom alleviationsymptom reductionsymptom relieftreatment as usualtreatment providerusual carevascular risk factorvideoconferencevideoconferences
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Description preview

Post-stroke depression (PSD) affects an estimated 33% of survivors. Subthreshold depression (SD; clinically
relevant depressive symptoms that do not meet diagnostic criteria for a clinical disorder) can affect up to 60% of

stroke survivors and, if untreated, likely progresses to PSD. PSD is associated with recurrent stroke, mortality

(including…

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BehavioraL ActIvation for the PreVention of Post-strokE Depression in LoW-incomE OLder Stroke Survivors (LIVE-WEL) — UNI | Dev Procure