grant
BDCRC - Career Enhancement Core
Organization HUGO W. MOSER RES INST KENNEDY KRIEGERLocation BALTIMORE, UNITED STATESPosted 15 Sept 2025Deadline 31 Aug 2030
NIHUS FederalResearch GrantFY2025AdvocacyAptitudeAwardAwarenessBatten DiseaseBatten-Mayou DiseaseBatten-Spielmeyer-Vogt DiseaseBiochemicalCLN2CLN2 geneCLN2 proteinCaringChildhoodClinicalClinical ResearchClinical StudyCollaborationsCommunitiesComplementComplement ProteinsDNA TherapyData AnalysesData AnalysisData Management CoreDegenerative Neurologic DisordersDevelopmentDiagnosticDiagnostic ErrorsDisabled PersonsDisabled PopulationDisciplineDiseaseDisease ManagementDisorderDisorder ManagementDisparity populationDysfunctionEducationEducational aspectsEnvironmentEthnic GroupEthnic PeopleEthnic PopulationEthnic individualEthnicity PeopleEthnicity PopulationFaceFacultyFamilyFellowshipFellowship ProgramFosteringFoundationsFunctional disorderFundingFutureGene Transfer ClinicalGeneticGenetic InterventionGoalsHandicappedHomeIndividualInstitutionInterdisciplinary ResearchInterdisciplinary StudyInvestigatorsJournalsJuvenile Cerebroretinal DegenerationKnowledgeLeadMagazineManuscriptsMentorsModelingMolecularMolecular GeneticsMultidisciplinary CollaborationMultidisciplinary ResearchNINDSNational Institute of Neurological Diseases and StrokeNational Institute of Neurological Disorders and StrokeNervous System Degenerative DiseasesNeural Degenerative DiseasesNeural degenerative DisordersNeurodegenerative DiseasesNeurodegenerative DisordersNeurologic Degenerative ConditionsNeurological disabilityNeuronal Ceroid-LipofuscinosisOrphan DiseasePatient advocacyPb elementPeople with DisabilitiesPersons with DisabilitiesPh D studentPh D. studentPh. D. studentPh.D studentPh.D. studentPhD studentPhD. studentPhysiopathologyPostdocPostdoctoral FellowProcessPublishingR-Series Research ProjectsR01 MechanismR01 ProgramRacial GroupRare DiseasesRare DisorderResearchResearch AssociateResearch GrantsResearch MethodologyResearch MethodsResearch PersonnelResearch Project GrantsResearch ProjectsResearch ResourcesResearch TrainingResearchersResidualResidual stateResourcesSample SizeSamplingScienceSiteSpielmeyer-Vogt DiseaseStructureSymptomsTechniquesTechnologyTestingTherapeuticTrainingTranslational ResearchTranslational ScienceVisual disabilityVisually disabledWorkadvocacy organizationscareercareer developmentceroid lipofuscinosisclinical immersionclinical outcome measuresclinical practiceclinical trainingclinical translationclinically translatablecomplementationdata interpretationdata management and coordinating centerdata management centerdegenerative diseases of motor and sensory neuronsdegenerative neurological diseasesdevelopmentaldiagnosis errorsdisabled individualdisabled peopledisadvantaged backgrounddisadvantaged groupdisadvantaged individualdisadvantaged peopledisadvantaged populationdisadvantaged subgroupdisparities across groupsdisparity across subgroupsdisparity among groupsdisparity among subgroupsdisparity between groupsdisparity between subgroupsdiversity, equity, and inclusivenessdoctoral studentequity, diversity, and inclusionethnic subgroupethnicity groupexperiencefacesfacialgender equitygene repair therapygene therapygene-based therapygenetic therapygenomic therapygroup disparitygroup inequalitygroup inequityheavy metal Pbheavy metal leadhereditary ceroid lipofuscinosishomesimprovedindividuals with disabilitiesinequalities among populationsinequalities between populationsinequalities in populationsinequality across populationsinequality among groupsinequality between groupsinequality in groupsinequities among populationsinequities between populationsinequities in populationsinequity across groupsinequity across populationsinequity between groupsinequity in groupsinnovateinnovationinnovativeinterestmarginalized backgroundmulti-modalitymultidisciplinarymultimodalityneurodegenerative illnessnext generationorphan disorderpathophysiologypatient advocacy grouppatient centeredpatient orientedpediatricpopulation inequalitypopulation inequitypost-docpost-doctoralpost-doctoral traineepre-docpre-doctoralpreventpreventingprogramsracial populationracial subgrouprecruitresearch and methodsresearch associatesresearch immersionskillssubgroup disparitytraining opportunitytranslation researchtranslational investigationunequal groupunequal populationvirtualvision disabilitywebinar
Description preview
CAREER ENHANCEMENT CORE – PROJECT SUMMARY/ABSTRACT
The neuronal ceroid lipofuscinoses (NCLs, Batten disease) are collectively the most prevalent childhood
neurodegenerative diseases. Despite a growing understanding of the molecular and cellular pathophysiology,
too few clinician investigators are conducting NCL translational research. This hinders…
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