grant

Archaeal Chromosome Dynamics

Organization OHIO STATE UNIVERSITYLocation Columbus, UNITED STATESPosted 1 Jan 2024Deadline 31 Dec 2028
NIHUS FederalResearch GrantFY2025ArchaeaArchaebacteriaArchaeobacteriaArchaeonArchitectureBiologic ModelsBiological ModelsCell BodyCellsChromosomesDNADNA Molecular BiologyDNA ReplicationDNA SynthesisDNA biosynthesisDeoxyribonucleic AcidEngineering / ArchitectureEnsureEpigeneticEpigenetic ChangeEpigenetic MechanismEpigenetic ProcessEukaryotaEukaryoteEvolutionGene ExpressionGene TranscriptionGenetic TranscriptionGenomeIn VitroLifeMediatingModel SystemMolecularMolecular BiologyMolecular ConfigurationMolecular ConformationMolecular StereochemistryPlanetsProcessProteinsRNA ExpressionRoleSulfolobalesSulfolobusSystemTranscriptionWorkconformationconformationalconformational stateconformationallyconformationsepigeneticallyin vivoinsightmicroorganismnovelsingle moleculesocial role
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Project Summary
My lab studies the molecular biology of archaeal microorganisms. Our rationale for doing so lies

in the evolutionary relationship between archaea and eukaryotes. Archaeal possess information

machineries that are in essence a simplified, ancestral version of the eukaryotic machinery.

Viewing these machineries through the prism of…

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