grant

Advancing computational modeling of disease metabolism by integrating AI and systems biology

Organization OREGON HEALTH & SCIENCE UNIVERSITYLocation PORTLAND, UNITED STATESPosted 25 Sept 2024Deadline 31 Aug 2029
NIHUS FederalResearch GrantFY2025AI AugmentedAI assistedAI drivenAI enhancedAI integratedAI poweredAbnormal Assessment of MetabolismAddressAreaArtificial Intelligence enhancedAugmented by AIAugmented by the AIAugmented with AIAugmented with the AIBiochemicalBiologyBiophysicsBody TissuesCancersCardiovascular DiseasesCell BodyCellsComplexComputational toolkitComputer ModelsComputerized ModelsDataDegenerative Neurologic DisordersDevelopmentDiabetes MellitusDietDiseaseDisorderEarly DiagnosisEarly treatmentGoalsHealthHeterogeneityImmune responseInflammatoryIntermediary MetabolismInterventionKnowledgeLiteratureMalignant NeoplasmsMalignant TumorMedicalMetabolicMetabolic PathwayMetabolic ProcessesMetabolic StudiesMetabolismMetabolism StudiesMethodologyMissionModelingMultiomic DataNIGMSNational Institute of General Medical SciencesNatural Language ProcessingNervous System Degenerative DiseasesNeural Degenerative DiseasesNeural degenerative DisordersNeurodegenerative DiseasesNeurodegenerative DisordersNeurologic Degenerative ConditionsNutrientNutritionalOrganismPathologyPatientsPopulationPreventionRecommendationResearchRoleSystemSystems BiologyTissuesTranscriptional ControlTranscriptional RegulationValidationVariantVariationartificial intelligence assistedartificial intelligence augmentedartificial intelligence drivenartificial intelligence integratedartificial intelligence poweredbiophysical foundationbiophysical principlesbiophysical sciencescardiovascular disorderclinical diagnosticscomputational modelingcomputational modelscomputational toolboxcomputational toolscomputational toolsetcomputer based modelscomputerized modelingcomputerized toolsdegenerative diseases of motor and sensory neuronsdegenerative neurological diseasesdesigndesigningdevelopmentaldiabetesdietarydietsdisease modeldisorder modelearly biomarkersearly detectionearly detection biomarkersearly detection markersearly therapyenhanced with AIenhanced with Artificial Intelligencehost responseimmune system responseimmunoresponseimprovedinnovateinnovationinnovativeinsightknowledge baseliving systemmalignancymedical diagnosticmetabolic abnormality assessmentmetabolic phenotypemetabotypemultiple omic datanatural language understandingneoplasm/cancerneural networkneurodegenerative illnessnew drug targetnew druggable targetnew pharmacotherapy targetnew therapeutic targetnew therapy targetnovelnovel drug targetnovel druggable targetnovel pharmacotherapy targetnovel therapeutic targetnovel therapy targetnutritiousprecision medicineprecision-based medicineresponsesocial roletherapy optimizationtooltreatment optimizationvalidations
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Project summary
Metabolic pathways are crucial for cellular energy and function. Dysregulated metabolism is a distinctive feature of

various diseases, including cancer, diabetes, cardiovascular disease, inflammatory, and neurodegenerative diseases.

Given its integral role in disease pathology, accurately and comprehensively characterizing…

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Advancing computational modeling of disease metabolism by integrating AI and systems biology — OREGON HEALTH & SCIENCE U | Dev Procure