grant
Advanced development and validation of aliquot-level visual indicators of biospecimen exposure to thawed conditions
Organization ARIZONA STATE UNIVERSITY-TEMPE CAMPUSLocation SCOTTSDALE, UNITED STATESPosted 8 May 2026Deadline 30 Apr 2029
NIHUS FederalResearch GrantFY2026ASCOAbscissionAcute NasopharyngitisAdvanced DevelopmentAgreementAliquotAmericanAmerican Society of Clinical OncologyArchivesBiologicalBiomedical ResearchBiopsyBlood PlasmaBlood SerumBody TissuesBooksBreast CancerCancersChemistryClinicalClinical ResearchClinical StudyCollectionColorCommon ColdCryofixationCryopreservationDataDepressed moodDevelopmentDevice DesignsDevicesERBB2ERBB2 geneElectronicsEstrogen ReceptorsExcisionExploratory/Developmental Grant for Diagnostic Cancer ImagingExposure toExtirpationFixationFreezingFundingGrantGuidelinesHER -2HER-2HER2HER2 GenesHER2/neuHistoryHourIndividualIndustrializationInvestigationInvestigatorsIschemiaKineticsLaboratoriesLaboratory PersonnelLiquid substanceMalignant Breast NeoplasmMalignant NeoplasmsMalignant TumorMarketingMeasurementMnO4MonitorNEU OncogeneNEU proteinNational Institutes of HealthOncogene ErbB2OncologistOperative ProceduresOperative Surgical ProceduresOxalatesPathologistPlasmaPlasma SerumProceduresQuality ControlR21 AwardRationalizationReactionRecording of previous eventsRemovalReportingResearchResearch PersonnelResearch SpecimenResearchersReticuloendothelial System, Serum, PlasmaRunningSamplingSerumSolventsSpecimenSpecimen HandlingSpecimen ProcessingSurgicalSurgical InterventionsSurgical ProcedureSurgical RemovalTIMP-1TKR1TemperatureTestingTimeTissue FixationTissue Inhibitor of Metalloproteinase-1TissuesTouchTouch sensationTranslatingUnited States National Institutes of HealthVEGFVEGFsValidationVascular Endothelial Growth FactorsVisualWhole BloodWorkaqueousbiologicc-erbB-2c-erbB-2 Genesc-erbB-2 Proto-Oncogenescell free DNAcell free circulating DNAchemical kineticscold preservationcold storagecold temperaturecollegecollegiatecommercializationcostdepresseddesigndesigningdevelopmentalelectronicelectronic deviceerbB-2 Genesestrogen receptor proteinestrophileestrophilinevidence baseexpirationfluidherstatinhigh riskhistoriesimprovedinnovateinnovationinnovativeinterestkinetics (chemistry)liquidlow temperaturemalignancymalignant breast tumormeltingneoplasm/cancerneu Genesperformance testspermanganateprogramsquality assuranceresectionsadnesssample fixationsimulationsuccesssurgerytactile sensationtooluser-friendlyvalidations
Description preview
Project Summary/Abstract
Many biological analytes of interest to both clinical oncologists and cancer researchers are unstable when the
unfixed biospecimens in which they reside are exposed to thawed conditions. For example, American Society
of Clinical Oncology / College of American Pathologists guidelines state that the…
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