grant
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Organization UNIVERSITY OF CALIFORNIA AT DAVISLocation DAVIS, UNITED STATESPosted 1 Aug 2023Deadline 31 Jul 2028
NIHUS FederalResearch GrantFY2025Academic Medical CentersAccountabilityAdministratorAnimalsBenchmarkingBest Practice AnalysisBioinformaticsBioinformatics coreBioinformatics research coreBioinformatics resource coreBudgetsCaliforniaCancer CenterCancer ModelCancer PatientCancer health equityCancerModelCancersCatchment AreaCertificationClinical ResearchClinical StudyCollaborationsCollectionCommunicationComplexComprehensive Cancer CenterData CommonsDecision MakingDepositDepositionDevelopmentDoctor of PhilosophyDocumentationEnsureFamilyFundingGastric Body CancerGastric CancerGastric Cardia CancerGastric Fundus CancerGastric NeoplasmsGastric Pylorus CancerGastric TumorGenerationsGeneticGenomicsGoalsGrantHealthHealth Disparities ResearchHealth disparities related researchHeterograftHeterologous TransplantationInfrastructureInstitutionInternationalInterruptionInvestigatorsLaboratoriesLeadershipLos AngelesLungLung NeoplasmsLung Respiratory SystemLung TumorMalignant Gastric NeoplasmMalignant Gastric TumorMalignant NeoplasmsMalignant TumorMalignant Tumor of the LungMalignant neoplasm of lungMapsMinorityModelingMonitorPDX modelPathway interactionsPatient derived xenograftPatientsPh.D.PhDPre-Clinical ModelPreclinical ModelsProceduresProductivityPulmonary CancerPulmonary NeoplasmsPulmonary malignant NeoplasmQuality ControlR-Series Research ProjectsR01 MechanismR01 ProgramRecommendationResearchResearch ActivityResearch GrantsResearch PersonnelResearch Project GrantsResearch ProjectsResearch ResourcesResearch SpecimenResearchersResourcesRoleSan FranciscoSiteSpecimenStomachStomach CancerStomach NeoplasmsStomach TumorTexasUniversitiesUniversity Medical CentersWorkXenograftXenograft ModelXenograft procedureXenotransplantationanti-cancer researchbenchmarkcancer disparitycancer health disparitycancer researchcancer typecancer-related health disparitydata exchangedata sharingdata transferdata transmissiondepositorydevelopmentaldisparity in cancerethnic diversityethnic minorityethnic minority groupethnic minority individualethnic minority peopleethnic minority populationethnically diverseexpectationexperimentexperimental researchexperimental studyexperimentsgastricgastric malignancyhealth disparities sciencehuman subjectindividualized cancer careindividualized oncologylung cancermalignancymalignant stomach neoplasmmalignant stomach tumormeetingmeetingsmemberminority patientneoplasm/cancernew drug treatmentsnew drugsnew pharmacological therapeuticnew therapeuticsnew therapynext generation therapeuticsnovel drug treatmentsnovel drugsnovel pharmaco-therapeuticnovel pharmacological therapeuticnovel therapeuticsnovel therapypathwaypatient derived xenograft modelpatients from minoritypatients of minoritypersonalized oncologypre-clinical researchprecision cancer careprecision cancer medicineprecision oncologypreclinical researchprogramsquality assuranceracial diversityracial minorityracial minority groupracial minority individualracial minority peopleracial minority populationracially diverserepositoryresponse to therapyresponse to treatmentsample collectionsocial rolespecimen collectionstomach fundus cancerstomach pylorus cancersuccesstargeted drug therapytargeted drug treatmentstargeted therapeutictargeted therapeutic agentstargeted therapytargeted treatmenttherapeutic responsetherapy responsetimelinetreatment responsetreatment responsivenessxeno-transplantxeno-transplantationxenograft transplant modelxenotransplant model
Description preview
PROJECT SUMMARY/ABSTRACT
The overall goal of this application is to establish and characterize a large collection of minority patient-derived
cancer xenografts (PDXs) from two cancer types (gastric and lung) and utilize these PDXs to guide cancer
precision medicine decision making focusing on racial/ethnic minority populations. We established the…
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