grant
Acute Kidney Injury in Care Transitions: The ACT Pragmatic Trial
Organization MAYO CLINIC ROCHESTERLocation ROCHESTER, UNITED STATESPosted 3 Mar 2026Deadline 31 Jan 2031
NIHUS FederalResearch GrantFY2026Academic Medical CentersAccess to CareAccess to InformationActive Follow-upAcute Kidney FailureAcute Kidney InsufficiencyAcute Renal FailureAcute Renal InsufficiencyAddressAdherenceAdverse drug eventAffectAreaBlood PressureBlood SerumCardiovascular DiseasesCaringChronic Kidney FailureChronic Renal DiseaseChronic Renal FailureClinicClinical TrialsCluster randomization trialCluster randomized trialCodeCoding SystemCreatinineDataDecision MakingDecrease health disparitiesDisease ProgressionDisparitiesDisparityDrugsEarly DiagnosisEducationEducational aspectsElectronicsElementsFaceGoalsGuidelinesHealthHealth InstructionHealth Services AccessibilityHealth TutoringHealth disparity mitigationHealth disparity reductionHealth educationHealth systemHomeHome environmentHospital AdmissionHospitalizationHospitalsIncidenceIndividualInterventionInterviewKidneyKidney DiseasesKidney Urinary SystemLaboratoriesLower health disparitiesMarylandMedicalMedicationMidwestMidwest U.S.Midwest USMidwestern United StatesMitigate health disparitiesModificationMonitorNephrologyNephropathyNephrotoxicNew EnglandNortheastern United StatesNursesOutcomePatient outcomePatient-Centered OutcomesPatient-Focused OutcomesPatientsPharmaceutical PreparationsPharmacistsPopulationPrimary CareProcessPrognosisProteinsProviderQOCQOLQualitative MethodsQualitative ResearchQuality of CareQuality of lifeRandomizedRecurrenceRecurrentReduce health disparitiesRenal DiseaseRenal functionRenin-Angiotensin SystemResearch ResourcesResourcesRiskRuralSGLT 2 inhibitorSGLT2iSamplingSerumService delivery modelService modelSodium glucose co-transporter 2 inhibitorSpecialistSpecialtyStratificationSupportive TherapySupportive careSurvivorsSymptomsSystemTabletsTechnologyTestingTransportationUnited StatesUniversitiesUniversity Medical CentersUrban CommunityUrineVisitaccess to health servicesaccess to servicesaccess to treatmentaccessibility to health servicesactive followupacute careacute kidney injuryavailability of servicesburden of diseaseburden of illnesscardiovascular disease riskcardiovascular disordercardiovascular disorder riskcare accesscare as usualcare deliverycare delivery modelcare resourceschronic kidney diseaseclinical riskco-morbidco-morbiditycomorbiditydigitaldigital healthdisease burdendisparity in healthdrug/agentearly detectioneducation resourceseducational resourceselectronicelectronic deviceevidence baseexperiencefacesfacialfollow upfollow-upfollowed upfollowuphealth care delivery modelhealth care resourceshealth disparityhealth literacyhealth service accesshealth services availabilityhigh riskhome based monitoringhome monitoringhomeshospital re-admissionhospital readmissionimprovedimproved outcomeinhibitorinjury recoveryinnovateinnovationinnovativeinsightkidney disorderkidney functionkidney toxicitylow SESlow socio-economic positionlow socio-economic statuslow socioeconomic positionlow socioeconomic statusmedical specialtiesmultidisciplinarynephrotoxicitynovelnurseoutreach to informationpatient centeredpatient orientedpatient oriented outcomespilot testpragmatic effectiveness trialpragmatic trialprimary care patientprimary care providerprimary outcomeprognosticationprogramsproviders from primary careproviders of primary carequalitative reasoningrandomisationrandomizationrandomly assignedre-admissionre-hospitalizationreadmissionrecovery after injuryrecovery following injuryrecovery post injuryrehospitalizationremote monitoringrenalrenal disorderrisk stratificationrural arearural localityrural locationrural patientsrural placerural regionrural settingservice availabilitysocial health determinantsstratify risksuburbsuburbansuburbiatreatment accesstreatment as usualusual care
Description preview
PROJECT SUMMARY/ABSTRACT
Acute kidney injury (AKI) is an abrupt loss of kidney function that affects 1 in 5 hospitalized patients. AKI
survivors experience a 1.5-2.5-fold higher risk of chronic kidney disease (CKD), a 1.4-fold higher risk of
cardiovascular disease, and 50% of affected individuals are readmitted within 1 year. Despite these grave…
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