grant
Absolute Brain Thermography using Multinuclear MRI
Organization NEW YORK UNIVERSITY SCHOOL OF MEDICINELocation NEW YORK, UNITED STATESPosted 1 Aug 2024Deadline 30 Apr 2028
NIHUS FederalResearch GrantFY20253-D3-Dimensional3DAccelerationAcquired brain injuryAddressAffectAmentiaAnimalsApoplexyArtifactsBindingBody TemperatureBody Temperature RegulationBody ThermoregulationBody TissuesBody WeightBrainBrain InjuriesBrain IschemiaBrain Nervous SystemBrain VascularBrain Vascular AccidentCardiopulmonaryCationsCause of DeathCell Communication and SignalingCell SignalingCerebral IschemiaCerebral StrokeCerebrovascular ApoplexyCerebrovascular CirculationCerebrovascular StrokeCerebrumChemicalsClinicalConsumptionCustomD-GlucoseDangerousnessDementiaDependenceDetectionDeteriorationDevelopmentDextroseDiseaseDisease OutcomeDisorderEncephalonEnvironmentExhibitsFeverFrequenciesGlucoseGoalsH+ elementHeatingHumanHydrogen IonsHyperthermiaImageImmunityImpairmentIntermediary MetabolismInterruptionIntracellular Communication and SignalingInvestigatorsIschemiaIschemic EncephalopathyLocal HyperthermiaMR ImagingMR SpectroscopyMR TomographyMRIMRIsMagnetic ResonanceMagnetic Resonance ImagingMagnetic Resonance SpectroscopyMeasurementMeasuresMediatingMedical Imaging, Magnetic Resonance / Nuclear Magnetic ResonanceMetabolicMetabolic ProcessesMetabolismModelingModern ManMolecular InteractionMonitorMorphologic artifactsMotionNMR ImagingNMR TomographyNa elementNeurologicNeurologicalNoiseNuclearNuclear Magnetic Resonance ImagingO elementO2 elementOutcomeOxygenPathologicPatientsPerformancePerfusionPeripheralPhasePhysiologicPhysiologic ThermoregulationPhysiologicalPredispositionProcessPrognostic MarkerProtonsPyrexiaRectumResearch PersonnelResearchersRiskRodentRodentiaRodents MammalsSeriesSignal TransductionSignal Transduction SystemsSignalingSodiumSourceSpeedStrokeSusceptibilityTechniquesTemperatureTestingThermographiesThermographyThermometryThermoregulationThrombotic StrokeTimeTissuesValidationVariantVariationZeugmatographybiological signal transductionblood flow in brainbrain attackbrain blood circulationbrain blood flowbrain damagebrain tissuebrain-injuredcerebralcerebral blood flowcerebral circulationcerebral vascularcerebral vascular accidentcerebro-vascularcerebrocirculationcerebrovascularcerebrovascular accidentcerebrovascular blood flowclinical practicecold temperaturecostcustomsdevelopmentaldiagnostic developmentdiagnostic tooldisabilityfebrilefebrishuman subjecthypoperfusionimagingimaging approachimaging based approachimaging spectroscopyimplantationimprovedin vivoischemia injuryischemic injurylow temperaturemagnetic fieldneuroimaging biomarkerneuroimaging markernon-human primatenonhuman primatenovelpreservationpreventpreventingprognostic biomarkerprognostic indicatorprognostic toolreconstructionspatial and temporalspatial temporalspatiotemporalspectroscopic imagingstandard carestandard treatmentstroke modelstroke patientstrokedstrokestherapeutic targetthermographic imagingthree dimensionalvalidationswasting
Description preview
PROJECT SUMMARY
Stroke is the leading cause of disability, the second leading cause of dementia, and the second leading
cause of death worldwide, affecting nearly 800,000 patients per annum in the U.S. alone. Cerebrovascular
ischemia is rapidly potentiated by rising body temperatures, occurring even with mild and sub-febrile
hyperthermia. The…
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