grant
A Type 2 Hybrid Effectiveness-Implementation Study of Time Limited Trials to Reduce Potentially Non-Beneficial Treatments for Critically Ill Patients with Advanced Medical Illnesses
Organization LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTERLocation TORRANCE, UNITED STATESPosted 25 Sept 2025Deadline 31 Aug 2030
NIHUS FederalResearch GrantFY2025AffectAgreementApplication ContextAreaAssess implementationCaliforniaCaringCharacteristicsClinical SciencesClinical TrialsClinical assessmentsCommunicationComplexConsensusConsolidated Framework for Implementation ResearchConsolidated Framework for Implementation ScienceConsolidated Framework for Implementing ChangeCountyCritical IllnessCritically IllDecision MakingEffectivenessEnvironmentEnvironmental FactorEnvironmental Risk FactorEquityFamilyFamily Care GiverFamily CaregiverGoalsHealth CareHealth Care SystemsHealth ServicesHealth Services EvaluationHealth Services ResearchHigh PrevalenceHospital AdministratorsHospital MortalityHospitalsImplementation assessmentIn-house MortalitiesIndigentInhospital MortalityInstitutionIntegrated Health Care SystemsIntensive Care UnitsInterventionIntervention StrategiesIntervention TrialInterventional trialInvestigatorsKidney Replacement TherapyKnowledgeLanguageLeadLength of StayLifeLos AngelesMechanical ventilationMedicalMedical Care ResearchMethodsNumber of Days in HospitalParticipantPatient AdmissionPatient PreferencesPatientsPb elementPhysiciansPilot ProjectsPrognosisProviderPublic HealthRE-AIMRaceRacesReach, Effectiveness, Adoption, Implementation, and MaintenanceRenal Replacement TherapyResearch PersonnelResearchersSocioeconomically disadvantagedSpecific qualifier valueSpecifiedStructureSystemTestingTimeTime StudyUncertaintyUnited StatesWorkassess effectivenesscare preferencecontextual factorscostdesigndesigningdetermine effectivenessdisparity in healthdoubteffectiveness assessmenteffectiveness evaluationeffectiveness/implementation hybrideffectiveness/implementation hybrid studyeffectiveness/implementation studyenvironmental riskethnic diversityethnically diverseevaluate effectivenessevaluate implementationevaluation of implementationexamine effectivenesshealth disparityhealth equityheavy metal Pbheavy metal leadhigh riskhospital carehospital dayshospital length of stayhospital stayimplementation evaluationimplementation frameworkimplementation outcomesimplementation processimplementation research frameworkimplementation scienceimplementation science frameworkimprovedinadequate health literacyintegrated health systemintegrated system of carelow health literacymechanical respiratory assistmechanically ventilatedmeetingmeetingsmembermortalitypatient centeredpatient orientedpatient populationpilot studypoor health literacypreferenceprimary outcomeracialracial backgroundracial diversityracial originracially diversereach, efficacy, adoption, implementation, and maintenancereduced health literacysatisfactionscale upsecondary analysisservices researchshared decision makingsocio-economicsocio-economic disadvantagesocio-economicallysocio-economically disadvantagedsocio-economically underprivilegedsocioeconomic disadvantagesocioeconomicallysocioeconomically underprivilegedsocioeconomicssurrogate decision makertime use
Description preview
Project Summary
Overutilization of invasive intensive care unit (ICU) treatments for patients with advanced medical
illnesses may lead to medical care that provides minimal benefit and prolongs suffering. Although the factors
that lead to overuse of potentially non-beneficial treatments are complex, an important contributor is poor
communication…
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