grant
A randomized, sham controlled clinical trial to assess the effectiveness of a positive end expiratory device for accelerating and maintaining pulmonary rehabilitation gains
Organization CINCINNATI VA MEDICAL CENTER RESEARCHLocation CINCINNATI, UNITED STATESPosted 1 Jan 2026Deadline 31 Dec 2029
VANIHUS FederalResearch GrantFY2026AccelerationAddressAffectAnxietyAreaBiofeedbackBreathingBreathing MechanicsBreathlessnessCOPDCardiacChronic Obstruction Pulmonary DiseaseChronic Obstructive Lung DiseaseChronic Obstructive Pulmonary DiseaseClinical TrialsConfusionConfusional StateControlled Clinical TrialsCost of IllnessCross-Over StudiesCrossover StudiesDataDevicesDisease CostsDouble-Blind MethodDouble-Blind StudyDouble-BlindedDouble-Masked MethodDouble-Masked StudyDropoutDyspneaEffectivenessEmotional DepressionEnrollmentErgometryEvaluationExerciseExercise PhysiologyFEV1FEV1%VCFEVtForced Expiratory VolumeForced Expiratory Volume 1 TestForced Expiratory Volume in 1 SecondForced expiratory volume functionFosteringGeneral PopulationGeneral PublicHigh PrevalenceHypoxiaHypoxicInterventionInvestigationLearningLung symptomMaintenanceMeasurementMedical RehabilitationMental ConfusionMental DepressionMonitorMoodsNon-pharmacologic TherapyNonpharmacologic InterventionNonpharmacologic TherapyNonpharmacologic approachNonpharmacologic treatmentO elementO2 elementOutcomeOutputOxygenOxygen DeficiencyPFT/FEV1ParticipantPatientsPerceptionPersonsPhysiologicPhysiologicalPlethysmographyProcessPulmonary Function Test/Forced Expiratory Volume 1QOLQOL improvementQuality of lifeQuestionnairesRandomizedRandomized, Controlled TrialsRecoveryRehabilitationRehabilitation OutcomeRehabilitation therapyRelaxationReportingResidualResidual stateRespiratory AspirationRespiratory InspirationRespiratory MechanicsRiskRunningSalivaSelf EfficacyShortness of BreathSickness CostSymptom BurdenSymptomsTechniquesTestingTidal VolumeTimeTimed Forced Vital CapacityTimed Vital CapacityTrainingUniversitiesVeteransWalkingWomanWorkactigraphactigraphyalleviate symptomameliorating symptomanxiety symptomsanxious symptomarmassess effectivenessasthma controllerasthma inhalerasthma relieverattenuationchronic obstructive pulmonary disorderchronic symptomcohortconditioningdaily functioningdecrease symptomdepressiondepression symptomdepressivedepressive symptomsdetermine effectivenesseffective interventioneffectiveness assessmenteffectiveness clinical trialeffectiveness evaluationenrollepidemiology research studyepidemiology studyepidemiology surveyevaluate effectivenessexamine effectivenessexperiencefallsfewer symptomsfunctional improvementfunctional independencefunctional statusimprove functionimprove symptomimprovedimproved functional outcomesimprovements in QOLimprovements in quality of lifeinnovateinnovationinnovativeinspirationlung rehabilitationmenmilitary veteranmortalitynon-drug therapynon-drug treatmentnondrug therapynondrug treatmentnovelpersistent symptomportabilitypressurepreventpreventingprogramspsychologicpsychologicalpulmonary rehabilitationpulmonary symptomquality of life improvementquality of sleeprandomisationrandomizationrandomized control trialrandomly assignedrecruitreduce symptomsrehab therapyrehabilitativerehabilitative outcomerehabilitative therapyrelieves symptomsrescue inhalerrespiratoryrespiratory airway volumeresponsesecondary outcomesleep qualitysymptom alleviationsymptom improvementsymptom reductionsymptom reliefsymptomatic improvementtoolusabilityuser-friendlyveteran populationwearablewearable devicewearable electronicswearable systemwearable technologywearable toolwearables
Description preview
Chronic Obstructive Pulmonary Disease (COPD) is a debilitating condition with a higher prevalence among
Veterans compared to the general population. Pulmonary rehabilitation (PR) represents the most effective non-
pharmaceutical treatment option for control of daily symptoms and promoting functional independence.
Successful completion of PR is…
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