grant

A novel drug discovery workflow combining DNA-encoded library, AI machine learning and cryo-electron microscopy

Organization UKRILocation United Kingdom
UKRIUK ResearchGrantActive
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Description preview

I am using a novel drug discovery workflow to identify small molecule compound hits for a metabolic enzyme, which has been implicated as a therapeutic target for rare genetic diseases, underpinned by inborn errors of metabolism. This approach aims to facilitate structure based drug discovery for targets recalcitrant to crystallography.

UKRI…

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A novel drug discovery workflow combining DNA-encoded library, AI machine learning and cryo-electron microscopy — UKRI | | Dev Procure